CAS 7729-94-4

Lidocaine impure Hydrochloride

Description:

Lidocaine impure hydrochloride, with the CAS number 7729-94-4, is a local anesthetic commonly used in medical applications to provide temporary pain relief. As a hydrochloride salt, it is typically more soluble in water than its base form, enhancing its bioavailability for injection or topical application. The substance is characterized by its white to off-white crystalline powder appearance and has a melting point that varies depending on purity. Lidocaine acts by blocking sodium channels in neuronal cell membranes, thereby inhibiting the initiation and conduction of nerve impulses. Impurities in the compound can arise from the synthesis process or storage conditions, potentially affecting its efficacy and safety profile. It is essential to handle lidocaine hydrochloride with care, as it can cause side effects such as allergic reactions or systemic toxicity if administered improperly. In pharmaceutical formulations, it is often combined with other agents to enhance its anesthetic effects or to prolong its duration of action. Proper quality control measures are crucial to ensure the safety and effectiveness of lidocaine hydrochloride in clinical use.

Norlidocaine Hydrochloride (Monoethylglycinexylidide Hydrochloride)

CAS: 7729-94-4

Color and Shape: Neat

Ref: 61-FOR0102.05

Norlidocaine Hydrochloride (N-(2,6-Dimethylphenyl)-2-(ethylamino)acetamide hydrochloride)

CAS: 7729-94-4

Cyclic amides and their derivatives, nesoi

Formula: C₁₂H₁₈N₂OHCl

Color and Shape: White Solid

Molecular weight: 206.14191

Ref: 45-1A12700

Norlidocaine HCl

CAS: 7729-94-4

Formula: C₁₂H₁₉ClN₂O

Purity: 98%

Color and Shape: Solid

Molecular weight: 242.7451

Ref: IN-DA00G4Z3

Lidocaine Impurity 1

CAS: 7729-94-4

Formula: C₁₁H₂₃N₃O₂

Color and Shape: Yellow Liquid

Molecular weight: 229.32

Ref: 4Z-L-0621

Lidocaine EP Impurity D HCl

CAS: 7729-94-4

Formula: C₁₂H₁₈N₂O·HCl

Color and Shape: White To Off-White Solid

Molecular weight: 206.29 36.46

Ref: 4Z-L-062

N-(2,6-Dimethylphenyl)-2-(ethylamino)acetamide hydrochloride

CAS: 7729-94-4

N-(2,6-Dimethylphenyl)-2-(ethylamino)acetamide hydrochloride

Purity: 98%

Molecular weight: 242.75g/mol

Ref: 54-OR87302

Lidocaine EP Impurity D (as Hydrochloride)

Controlled Product

CAS: 7729-94-4

Formula: C₁₂H₁₈N₂O·ClH

Color and Shape: Neat

Molecular weight: 242.75

Ref: 86-MM0102.05

Norlidocaine Hydrochloride

CAS: 7729-94-4

Formula: C₁₂H₁₈N₂O·HCl

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 242.75

Ref: 3B-N1171

Nor Lidocaine-d6 Hydrochloride

Controlled Product

CAS: 7729-94-4

Applications Nor Lidocaine-d6 Hydrochloride is the labeled analogue of Nor Lidocaine Hydrochloride (N713500), a hydrochloride salt metabolite of Lidocaine (L397800), a local anesthetic; antiarrhythmic (class IB). Long-acting, membrane stabilizing agent against ventricular arrhythmia. Originally developed as a local anesthetic.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Fukuda, S., et al.: Anesthesiology, 53, 106 (1980); Duce, R., et al.: J. Pharmacol. Exp. Ther., 179, 580 (1971); Kronberg, G.H., et al.: J. Med. Chem., 16, 739 (1973); Groningsson, K., et al.: Anal. Profiles Drug Subs., 14, 207 (1985); Davies, P.S., et al.: Drugs, 64, 937 (2004)

Formula: C₁₂H₁₃D₆ClN₂O

Color and Shape: Neat

Molecular weight: 248.78

Ref: TR-N713503

Nor Lidocaine Hydrochloride

Controlled Product

CAS: 7729-94-4

Impurity Lidocaine EP Impurity D (HCl)
Applications Nor Lidocaine Hydrochloride is a hydrochloride salt metabolite of Lidocaine (L397800), an Anesthetic (local); antiarrhythmic (class IB). Long-acting, membrane stabilizing agent against ventricular arrhythmia. Originally developed as a local anesthetic
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Fukuda, S., et al.: Anesthesiology, 53, 106 (1980), Duce, R., et al.: J. Pharmacol. Exp. Ther., 179, 580 (1971); Kronberg, G.H., et al.: J. Med. Chem., 16, 739 (1973); Groningsson, K., et al.: Anal. Profiles Drug Subs., 14, 207 (1985); Davies, P.S., et al.: Drugs, 64, 937 (2004);

Formula: C₁₂H₁₈N₂O·ClH

Color and Shape: White To Off-White

Molecular weight: 242.75

Ref: TR-N713500

N-(2,6-Dimethylphenyl)-2-(ethylamino)acetamide hydrochloride

CAS: 7729-94-4

Purity: 98%

Molecular weight: 242.75

Ref: 10-F692666

Nor Lidocaine-d6 Hydrochloride

CAS: 7729-94-4

Nor Lidocaine-d6 Hydrochloride is a chromatographic reference standard for the quantitative analysis of lidocaine. It has been extensively used in the metabolism studies of hepatic cytochrome P450, anova studies, and in vivo pharmacokinetic experiments with animals. The half-life values of lidocaine are dependent on the animal species being studied, but terminal half-life values are generally between 2.5 and 5 hours. Nor Lidocaine-d6 Hydrochloride can be used as a reference standard for high specificity liquid chromatography methods and HPLC techniques. In vitro studies have shown that Nor Lidocaine-d6 Hydrochloride is metabolized by the p450 system, which may be due to its hydrolysis by hydrochloric acid.

Formula: C₁₂H₁₃D₆ClN₂O

Purity: Min. 95%

Molecular weight: 248.78 g/mol

Ref: 3D-HAA72994