CAS 77337-73-6

Acamprosate calcium

Description:

Acamprosate calcium is a chemical compound primarily used in the treatment of alcohol dependence. It acts as a modulator of the neurotransmitter systems in the brain, particularly by influencing glutamate and gamma-aminobutyric acid (GABA) pathways, which are crucial for maintaining a balance in neuronal excitability. The substance is typically presented as a white to off-white crystalline powder, soluble in water, and has a relatively stable structure under standard conditions. Its molecular formula includes calcium, which contributes to its stability and solubility characteristics. Acamprosate calcium is often administered in tablet form and is known for its role in reducing cravings and supporting abstinence in individuals recovering from alcohol use disorder. The compound is generally well-tolerated, with a side effect profile that may include gastrointestinal disturbances. As with any medication, it is essential for users to consult healthcare professionals for appropriate usage and potential interactions with other substances.

Formula: C₁₀H₂₀CaN₂O₈S₂

InChI: InChI=1/2C5H11NO4S.Ca/c2*1-5(7)6-3-2-4-11(8,9)10;/h2*2-4H2,1H3,(H,6,7)(H,8,9,10);/q;;+2/p-2

InChI key: InChIKey=FQYZCUOYXXIDPF-UHFFFAOYSA-N

SMILES: C(CNC(C)=O)CS(=O)(=O)O.[Ca]

Synonyms:

• 1-Propanesulfonic acid, 3-(acetylamino)-, calcium salt (2:1)
• Alcomed
• Aotal
• Ca-AOTA
• Calcium 3-(acetylamino)propane-1-sulfonate
• Calcium Bis[3-(Acetylamino)Propane-1-Sulfonate]
• Calcium N-acetylhomotaurinate
• Calcium acamprosate
• Calcium bisacetyl homotaurine
• Calcium(2+) 3-(acetylamino)propanesulphonate
• Campral
• Campral EC
• Regtect
• Sobriol
• Unii-59375N1D0U
• Acamprosate calcium
• 3-(Acetylamino)-1-propanesulfonic acid calcium salt (2:1)
• Bis[3-(acetylamino)-1-propanesulfonic acid]calcium salt
• 3-(Acetylamino)-1-propanesulfonic Acid Calcium Salt, Calcium Acetylhomotaurine
• 3-(ACETYLAMINO)-1-PROPANESULFONIC ACID CALCIUM SALT
• CALCIUM ACETYLHOMOTAURINE
• Calcium acetylhomotaurinate
• calcium 3-acetamidopropane-1-sulfonate
• ALAMPROSATECALCIUM
• calcium 3-(acetylamino)propanesulphonate
• CaAOTA

Acamprosate Calcium

CAS: 77337-73-6, 77337-76-9

Formula: C₁₀H₂₀CaN₂O₈S₂

Purity: >98.0%(HPLC)

Color and Shape: White to Almost white powder to crystaline

Molecular weight: 400.47

Ref: 3B-A2359

Acamprosate calcium

CAS: 77337-73-6

Acamprosate calcium

Formula: C₁₀H₂₀CaN₂O₈S₂

Purity: 100%

Color and Shape: White. To. Off-White

Molecular weight: 400.0287

Ref: 47-1172

ACAMPROSATE CALCIUM CRS

CAS: 77337-73-6

ACAMPROSATE CALCIUM CRS

Ref: 41-Y0002199

Acamprosate Calcium

CAS: 77337-73-6

Acyclic amides (including acyclic carbamates) and their derivatives and salts thereof, nesoi

Formula: C₁₀H₂₀N₂O₈S₂Ca

Color and Shape: Powder

Molecular weight: 400.0287

Ref: 45-1000554

Acamprosate Calcium

CAS: 77337-73-6

Formula: C₁₀H₂₀CaN₂O₈S₂

Purity: 97%

Color and Shape: Solid

Molecular weight: 400.4824

Ref: IN-DA003NM1

Acamprosate Calcium Salt (Acetyl Homotaurine Calcium Salt)

CAS: 77337-73-6

Formula: C₅H₁₀NO₄S·Ca

Color and Shape: White To Off-White Solid

Molecular weight: 2*180.20 40.08

Ref: 4Z-A-156

Acamprosate calcium salt

CAS: 77337-73-6

Formula: C₅H₁₀Ca₀·5NO₄S

Molecular weight: 200.24

Ref: 7W-GK0896

Acamprosate calcium

CAS: 77337-73-6

Acamprosate calcium

Purity: ≥98%

Molecular weight: 400.48g/mol

Ref: 54-BUP11842

Acamprosate Calcium

CAS: 77337-73-6

Acamprosate Calcium

Purity: 98%

Molecular weight: 400.47g/mol

Ref: 54-IN11785

Acamprosate calcium

CAS: 77337-73-6

Acamprosate calcium (Campral EC) is a GABA receptor agonist and modulator of glutamatergic systems, used for treating alcohol dependence.

Formula: C₁₀H₂₀CaN₂O₈S₂

Purity: 98% - 99.93%

Color and Shape: White Odorless Or Nearly Odorless Powder

Molecular weight: 400.48

Ref: TM-T1673

Acamprosate Calcium

Controlled Product

CAS: 77337-73-6

Applications Acamprosate is a synthetic amino acid and a neurotransmitter analogue that is used as an alcohol deterrent in management of alcohol dependence and abuse. Acamprosate was approved for use in the therapy of alcohol dependence and abuse in the United States in 2004.
References Gerra, G., et al.: Neuroendocrinology Letters, 14, 119 (1992), Spanagel, R., et al.: Psychopharmacology, 139, 39 (1998), Schneider, U., et al.: Pharmacopsychiatry, 31, 110 (1998),

Formula: C₅H₁₀NO₄S·Ca

Color and Shape: Neat

Molecular weight: 400.48

Ref: TR-A120000

Acamprosate calcium

CAS: 77337-73-6

GABA receptor agonist; threatment for alcohol dependence

Formula: C₁₀H₂₀CaN₂O₈S₂

Purity: Min 98%

Color and Shape: White Powder

Molecular weight: 400.48 g/mol

Ref: 3D-FA16906

Acamprosate calcium salt - Bio-X ™

CAS: 77337-73-6

Acamprosate is a drug that has been shown to have a synergic effect in the treatment of alcohol dependence. It is a structural analogue of the neurotransmitter gamma-aminobutyric acid (GABA). Acamprosate works by binding to glutamate receptors and inhibiting the release of glutamate, which may help restore the balance between excitatory and inhibitory neurotransmitters in the brain. Acamprosate also has a protective effect on brain cells by inhibiting protein synthesis and increasing the production of glutathione, which acts as an antioxidant.

Formula: C₁₀H₂₀CaN₂O₈S₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 400.48 g/mol

Ref: 3D-BA164134