CAS 77369-21-2

L-Histidyl-L-arginine

Description:

L-Histidyl-L-arginine, with the CAS number 77369-21-2, is a dipeptide composed of the amino acids histidine and arginine. This compound features a peptide bond linking the carboxyl group of histidine to the amino group of arginine. L-Histidyl-L-arginine is known for its potential biological activities, including roles in nitric oxide synthesis and modulation of immune responses. It is typically soluble in water due to the presence of polar side chains, which enhances its bioavailability in physiological conditions. The presence of both basic (arginine) and imidazole-containing (histidine) side chains contributes to its buffering capacity, making it relevant in biochemical applications. Additionally, this dipeptide may exhibit antioxidant properties and has been studied for its potential therapeutic effects in various health conditions. Overall, L-Histidyl-L-arginine serves as an important molecule in biochemistry and pharmacology, with implications for nutrition and health.

Formula: C₁₂H₂₁N₇O₃

InChI: InChI=1S/C12H21N7O3/c13-8(4-7-5-16-6-18-7)10(20)19-9(11(21)22)2-1-3-17-12(14)15/h5-6,8-9H,1-4,13H2,(H,16,18)(H,19,20)(H,21,22)(H4,14,15,17)/t8-,9-/m0/s1

InChI key: InChIKey=NIKBMHGRNAPJFW-IUCAKERBSA-N

SMILES: C([C@@H](C(N[C@@H](CCCNC(=N)N)C(O)=O)=O)N)C1=CN=CN1

Synonyms:

• 11: PN: EP2161028 PAGE: 10 claimed protein
• 1705: PN: WO2007124090 PAGE: 83 claimed protein
• 348: PN: WO2009046220 SEQID: 348 claimed protein
• 36: PN: WO2020097235 SEQID: 265 claimed protein
• <span class="text-smallcaps">L</smallcap>-Arginine, <smallcap>L</span>-histidyl-
• <span class="text-smallcaps">L</smallcap>-Arginine, N²-<smallcap>L</span>-histidyl-
• <span class="text-smallcaps">L</smallcap>-Histidyl-<smallcap>L</span>-arginine
• Arginine, N²-histidyl-
• H-His-Arg-OH
• Arginine, N2-histidyl-
• L-Arginine, L-histidyl-
• L-Arginine, N2-L-histidyl-

H-His-Arg-OH

CAS: 77369-21-2

Formula: C₁₂H₂₁N₇O₃

Molecular weight: 311.3402

Ref: IN-DA00G4A8

H-His-Arg-OH trifluroacetate

CAS: 77369-21-2

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Formula: C₁₂H₂₁N₇O₃•(C₂HF₃O₂)x

Purity: Min. 95%

Color and Shape: Powder

Ref: 3D-FH183688

H-His-Arg-OH

CAS: 77369-21-2

H-His-Arg-OH is a synthetic peptide that has been shown to have cytotoxic effects on mammalian cells. The H-His-Arg-OH peptide can be used for the treatment of heart disease and autoimmune diseases, such as rheumatoid arthritis. This peptide has been found to be resistant to congestive heart failure, which is caused by a number of factors, including hypertension and valvular stenosis. It has also been shown to have an immunoglobulin G1 (IgG1) genotype.

Formula: C₁₂H₂₁N₇O₃

Purity: Min. 95%

Molecular weight: 311.34 g/mol

Ref: 3D-FH108062