CAS 77378-06-4

3′-Deoxy-N-(1-oxododecyl)adenosine

Description:

3′-Deoxy-N-(1-oxododecyl)adenosine is a modified nucleoside derivative of adenosine, characterized by the presence of a dodecyl chain at the nitrogen position of the adenine base. This modification enhances its lipophilicity, which can influence its biological activity and membrane permeability. The compound features a 3′-deoxy modification, indicating the absence of a hydroxyl group at the 3′ position of the ribose sugar, which can affect its stability and interaction with nucleic acids. The presence of the oxododecyl group suggests potential applications in drug delivery systems or as a biochemical probe due to its amphiphilic nature. The molecular structure allows for various interactions with biological membranes, potentially facilitating cellular uptake. Additionally, the compound may exhibit unique pharmacological properties, making it of interest in medicinal chemistry and biochemistry research. As with many nucleoside analogs, its synthesis and characterization are crucial for understanding its potential therapeutic applications and mechanisms of action.

Formula: C₂₂H₃₅N₅O₄

InChI: InChI=1S/C22H35N5O4/c1-2-3-4-5-6-7-8-9-10-11-18(30)26-20-19-21(24-14-23-20)27(15-25-19)22-17(29)12-16(13-28)31-22/h14-17,22,28-29H,2-13H2,1H3,(H,23,24,26,30)/t16-,17+,22+/m0/s1

InChI key: InChIKey=SMLBNGQUSUEUEO-GSHUGGBRSA-N

SMILES: N(C(CCCCCCCCCCC)=O)C1=C2C(N(C=N2)[C@@H]3O[C@H](CO)C[C@H]3O)=NC=N1

Synonyms:

• 3′-Deoxy-N-(1-oxododecyl)adenosine
• Adenosine, 3′-deoxy-N-(1-oxododecyl)-
• 3′-Deoxy-N-lauroyladenosine

3''-Deoxy-N6-lauroyladenosine

CAS: 77378-06-4

Ref: 7W-GN1315

N6-Lauroyl Cordycepin-d23

Controlled Product

CAS: 77378-06-4

Applications A novel labelled N6-substituted Cordycepin derivative; an adenosine deaminase inhibitor.
References Johns, D., et al.: Biochem. Pharmacol., 25, 1441 (1976), Muller, W., et al.: Cancer Res., 37, 3824 (1977), Sugar, A., et al.: Antimicrob. Agents Chemother., 42, 1424 (1998), Zhou, X., et al.: Eur. J. Pharmacol., 453, 309 (2002),

Formula: C₂₂D₂₃H₁₂N₅O₄

Color and Shape: Off-White

Molecular weight: 456.686

Ref: TR-L185502

N6-Lauroyl Cordycepin

Controlled Product

CAS: 77378-06-4

Applications A novel N6-substituted Cordycepin derivative; an adenosine deaminase inhibitor.
References Johns, D., et al.: Biochem. Pharmacol., 25, 1441 (1976), Muller, W., et al.: Cancer Res., 37, 3824 (1977), Sugar, A., et al.: Antimicrob. Agents Chemother., 42, 1424 (1998), Zhou, X., et al.: Eur. J. Pharmacol., 453, 309 (2002),

Formula: C₂₂H₃₅N₅O₄

Color and Shape: Neat

Molecular weight: 433.54

Ref: TR-L185500

3'-Deoxy-N6-lauroyladenosine

CAS: 77378-06-4

3'-Deoxy-N6-lauroyladenosine is a nucleoside analog that is used to treat cancer. It is a phosphoramidite compound and it has been shown to be highly active against cancer cells. 3'-Deoxy-N6-lauroyladenosine is an antiviral agent that inhibits viral DNA synthesis by competing with the natural substrate, deoxyribonucleosides, for incorporation into the growing DNA chain. It also prevents the replication of RNA viruses by inhibiting their transcription and translation processes. 3'-Deoxy-N6-lauroyladenosine also inhibits inflammation in the body and may act as a chemotherapeutic agent in other diseases such as diabetes, Alzheimer's disease, and Parkinson's disease.

Formula: C₂₂H₃₅N₅O₄

Purity: Min. 95%

Molecular weight: 433.54 g/mol

Ref: 3D-ND10014