Diethyl malonate-1,3-^13C2 is a labeled isotopomer of diethyl malonate, a versatile compound widely used in organic synthesis, particularly in the preparation of various esters and as a building block in the synthesis of pharmaceuticals and agrochemicals. The presence of the stable carbon isotopes (^13C) at the 1 and 3 positions allows for applications in tracer studies and metabolic research, providing insights into metabolic pathways and mechanisms. Diethyl malonate itself is a colorless liquid with a fruity odor, exhibiting good solubility in organic solvents. It has a relatively low boiling point and is characterized by its ability to undergo various chemical reactions, including esterification and malonic ester synthesis. The compound is generally stable under standard conditions but should be handled with care due to its potential reactivity and the presence of ester functional groups. As with many organic compounds, appropriate safety measures should be taken when handling diethyl malonate-1,3-^13C2, including the use of personal protective equipment and working in a well-ventilated area.

diethyl malonate-1,3-13C2

77386-82-4: Diethyl malonate-1,3-^13C2 is a labeled isotopomer of diethyl malonate, a versatile compound widely used in organic synthesis, particularly in the preparation of various esters and as a building block in the synthesis of pharmaceuticals and agrochemicals. The presence of the stable carbon isotopes (^13C) at the 1 and 3 positions allows for applications in tracer studies and metabolic research, providing insights into metabolic pathways and mechanisms. Diethyl malonate itself is a colorless liquid with a fruity odor, exhibiting good solubility in organic solvents. It has a relatively low boiling point and is characterized by its ability to undergo various chemical reactions, including esterification and malonic ester synthesis. The compound is generally stable under standard conditions but should be handled with care due to its potential reactivity and the presence of ester functional groups. As with many organic compounds, appropriate safety measures should be taken when handling diethyl malonate-1,3-^13C2, including the use of personal protective equipment and working in a well-ventilated area.

<p>Applications A labelled diethyl ester of malonic acid which occurs naturally in grapes and strawberries. It is used in the preparation of barbiturates, artificial flavourings, vitamin B1, and vitamin B6 as well as in perfumes. Propanedioic-1,3-13C2 Acid Diethyl Ester is used in the preparation of streptothricin and labeled fatty acids.<br>References Kasumov, T. &amp; Brunengraber, H.: J. Labelled Compd. Rad., 49, 171 (2006); Martinkus, K. et al.: Tetrahedron., 39, 3493 (1983); Svhreier, P. et al.: J. Agric. Food. Chem., 27, 365 (1979); Opdyke, D.L.J.: Food Cosm. Toxicol., 14, 745 (1976)<br></p>

CAS 77386-82-4

diethyl malonate-1,3-13C2

Diethyl Malonate-13C2

Ref: TR-D444423