CAS 77395-10-9

1H-Indole-2,3-dione,5-bromo-7-methyl-

Description:

1H-Indole-2,3-dione, 5-bromo-7-methyl- is a chemical compound that belongs to the indole family, characterized by its bicyclic structure consisting of a benzene ring fused to a pyrrole ring. This compound features a dione functional group, indicating the presence of two carbonyl (C=O) groups, which contribute to its reactivity and potential biological activity. The bromine atom at the 5-position and the methyl group at the 7-position introduce specific steric and electronic effects, influencing the compound's properties and interactions. Typically, indole derivatives exhibit a range of biological activities, including antimicrobial and anticancer properties, making them of interest in pharmaceutical research. The presence of halogens, such as bromine, can enhance the lipophilicity and bioavailability of the compound. Additionally, the compound's stability, solubility, and reactivity can vary based on the substituents and the overall molecular structure. As with many indole derivatives, it may also participate in various chemical reactions, including electrophilic substitutions and nucleophilic attacks, making it a versatile building block in organic synthesis.

Formula: C₉H₆BrNO₂

Synonyms:

• Isatin,5-bromo-7-methyl- (2CI)
• AURORA 18112
• 7-Methyl-5-broMoisatin
• 5-BROMO-7-METHYLISATIN
• 5-BroMo-7-Methylindoline-2,3-dione
• 5-BROMO-7-METHYL-1H-INDOLE-2,3-DIONE
• TIMTEC-BB SBB002521
• BUTTPARK 76\07-22
• 1H-indole-2,3-dione, 5-bromo-7-methyl-

5-Bromo-7-methylindoline-2,3-dione

CAS: 77395-10-9

Formula: C₉H₆BrNO₂

Purity: 96%

Color and Shape: Solid

Molecular weight: 240.0534

Ref: IN-DA005BK4

5-Bromo-7-methylindoline-2,3-dione

CAS: 77395-10-9

5-Bromo-7-methylindoline-2,3-dione

Purity: 98%

Molecular weight: 240.05g/mol

Ref: 54-OR90153

5-Bromo-7-methyl-1H-indole-2,3-dione

CAS: 77395-10-9

5-Bromo-7-methyl-1H-indole-2,3-dione is a lead compound that inhibits the inosine monophosphate (IMP) deaminase enzyme. This compound is an inhibitor of the IMP deaminase enzyme and has been shown to reduce viral load in HIV patients. 5-Bromo-7-methyl-1H-indole-2,3-dione has been studied as a potential treatment for other diseases such as mycophenolic acid renal toxicity and inflammatory bowel disease. This molecule is a regiospecific inhibitor of the IMPDE4 protein with IC50 values of 0.5 μM and 2 μM for the wild type and mutant forms respectively.

Formula: C₉H₆BrNO₂

Purity: Min. 95%

Color and Shape: Orange Powder

Molecular weight: 240.05 g/mol

Ref: 3D-FB70055

5-Bromo-7-methylindoline-2,3-dione

CAS: 77395-10-9

Formula: C₉H₆BrNO₂

Purity: 96%

Color and Shape: Solid

Molecular weight: 240.056

Ref: 10-F320168

5-Bromo-7-methyl-1H-indole-2,3-dione

Controlled Product

CAS: 77395-10-9

Applications 5-bromo-7-methyl-1h-indole-2,3-dione (cas# 77395-10-9) is a useful research chemical.

Formula: C₉H₆NO₂Br

Color and Shape: Neat

Molecular weight: 240.05

Ref: TR-B677805