CAS 77422-99-2

PD 90780

Description:

PD 90780, with the CAS number 77422-99-2, is a chemical compound that is primarily recognized for its application in various industrial processes, particularly in the field of catalysis. While specific characteristics may vary based on its formulation and intended use, PD 90780 is generally noted for its stability and effectiveness as a catalyst in organic reactions. It may exhibit properties such as a specific melting point, solubility in various solvents, and reactivity with certain functional groups, which are essential for its role in facilitating chemical transformations. Additionally, safety data sheets (SDS) for PD 90780 would provide crucial information regarding its handling, potential hazards, and environmental impact. As with any chemical substance, proper safety precautions should be observed when working with PD 90780 to mitigate risks associated with exposure or accidental release. For precise applications and characteristics, consulting technical data sheets or peer-reviewed literature is recommended.

Formula: C₁₉H₁₄N₄O₄

Synonyms:

• 7-(BENZOYLAMINO)-4,9-DIHYDRO-4-METHYL-9-OXO-PYRAZOLO[5,1-B]QUINAZOLINE-2-CARBOXYLIC ACID
• PD 90780
• Pyrazolo[5,1-b]quinazoline-2-carboxylic acid, 7-(benzoylamino)-4,9-dihydro-4-methyl-9-oxo-
• IAZAGXDMMVWYKF-UHFFFAOYSA-N

PD90780

CAS: 77422-99-2

Formula: C₁₉H₁₄N₄O₄

Purity: 98%

Molecular weight: 362.3389

Ref: IN-DA01E5A2

PD 90780

CAS: 77422-99-2

PD 90780

Purity: ≥98%

Molecular weight: 362.34g/mol

Ref: 54-BUP04194

PD 90780

CAS: 77422-99-2

PD 90780, a non-peptide NGF antagonist, blocks NGF/p75NTR binding; IC50: 23.1 µM (PC12), 1.8 µM (PC12nnr5).

Formula: C₁₉H₁₄N₄O₄

Purity: 99.22%

Color and Shape: Solid

Molecular weight: 362.34

Ref: TM-T12384

PD 90780

Controlled Product

CAS: 77422-99-2

Formula: C₁₉H₁₄N₄O₄

Color and Shape: Neat

Molecular weight: 362.34

Ref: TR-P217405

PD 90780

CAS: 77422-99-2

PD 90780 is a potent inhibitor of the ubiquitin-proteasome system, which plays a major role in the degradation of polypeptides. The ubiquitin-proteasome system has been implicated in the degradation of neurotrophins, growth factors and other signaling molecules. PD 90780 also inhibits transcription factor receptor activity and messenger RNA synthesis. It was found to be an antigen for immunological assays. PD 90780 blocks tumor cell growth by interfering with protein synthesis and blocking the activation of factor receptors. This drug also inhibits the production of polypeptides that are required for DNA synthesis, leading to cell death by apoptosis or necrosis.

Formula: C₁₉H₁₄N₄O₄

Purity: Min. 95%

Molecular weight: 362.34 g/mol

Ref: 3D-CDA42299