CAS 774596-24-6

2,3,5,6-tetradeuteriopyridine-4-carbohydrazide

Description:

2,3,5,6-Tetradeuteriopyridine-4-carbohydrazide is a chemical compound characterized by its unique structure, which includes a pyridine ring substituted with a carbohydrazide functional group. The presence of deuterium atoms, indicated by the prefix "tetradeutero," suggests that this compound is a labeled version of pyridine-4-carbohydrazide, where four hydrogen atoms have been replaced with deuterium isotopes. This substitution can significantly influence the compound's physical and chemical properties, such as its stability, reactivity, and isotopic behavior in various reactions. The compound is likely to be used in research applications, particularly in studies involving isotopic labeling, which can aid in tracking reaction pathways or understanding mechanisms in organic chemistry. Additionally, the hydrazide functional group may impart biological activity, making it of interest in medicinal chemistry. Overall, 2,3,5,6-tetradeuteriopyridine-4-carbohydrazide is a specialized compound with applications in both synthetic and analytical chemistry.

Formula: C₆H₃D₄N₃O

InChI: InChI=1/C6H7N3O/c7-9-6(10)5-1-3-8-4-2-5/h1-4H,7H2,(H,9,10)/i1D,2D,3D,4D

SMILES: c1(c(nc(c(c1C(=O)NN)[2H])[2H])[2H])[2H]

Synonyms:

• (< sup> 2< /sup> H< sub> 4< /sub> )Pyridine-4-carbohydrazide
• 4-Pyridine-D< Sub> 4< /Sub> -Carboxylic Acid, Hydrazide

Isoniazid-d4

CAS: 774596-24-6

Isoniazid-d4

Purity: ≥95%

Molecular weight: 141.16g/mol

Ref: 54-BUP21697

Isoniazid-d4 (Isonicotinoyl-d4 Hydrazide)

CAS: 774596-24-6

Formula: C₆H₃D₄N₃O

Color and Shape: White To Off-White Solid

Molecular weight: 141.17

Ref: 4Z-I-222

Isonicotinoyl-d4-hydrazide

CAS: 774596-24-6

Purity: 98 atom % D

Color and Shape: White Solid

Molecular weight: 141.17

Ref: 3U-D6924

Isoniazid-d4

CAS: 774596-24-6

Isoniazid-d4 is a deuterium isotope marker for Isoniazid.Isoniazid is a prodrug that must be activated by the bacterial peroxidase KatG, and is bactericidal.

Formula: C₆H₃D₄N₃O

Color and Shape: Solid

Molecular weight: 141.16

Ref: TM-TMIJ-0309

Isoniazid-d4

Controlled Product

CAS: 774596-24-6

Applications Labelled Isoniazid. Antibiotic for treatment of Mycobacterium tuberculosis, inhibits mycolic acid biosynthesis. Metabolized by hepatic N-acetyltransferase (NAT) and cytochrome P450 2E1 (CYP2E1) to form hepatotoxins. Selectively induces expression of CYP2E1. Reversibly inhibits CYP2C19 and CYP3A4 activities, and mechanistically inactivates CYP1A2, CYP2A6, CYP2C19 and CYP3A4 at clinically relevant concentrations. Antibacterial (tuberculostatic).
References Brewer, G.A., et al.: Anal. Profiles Drug Subs., 6, 183 (1977), Weber, W.W., et al.: Clin. Pharmacokinet., 4, 401 (1979)

Formula: C₆₂H₄H₃N₃O

Color and Shape: White To Light Beige

Molecular weight: 141.16

Ref: TR-I821452