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CAS 77465-10-2

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adrenocorticotropic hormone rat

Description:
Adrenocorticotropic hormone (ACTH) in rats, identified by the CAS number 77465-10-2, is a peptide hormone produced by the anterior pituitary gland. It plays a crucial role in the regulation of the adrenal cortex, stimulating the secretion of glucocorticoids, particularly cortisol, which is vital for stress response, metabolism, and immune function. ACTH is composed of 39 amino acids and is part of the larger pro-opiomelanocortin (POMC) precursor. Its secretion is regulated by corticotropin-releasing hormone (CRH) from the hypothalamus, responding to stress and circadian rhythms. In terms of physical characteristics, ACTH is typically a white to off-white powder that is soluble in water. The hormone's biological activity is mediated through its interaction with specific receptors on adrenal cells, leading to various physiological effects. Research on ACTH in rats provides insights into its role in stress physiology and potential implications for understanding human disorders related to adrenal function.
Formula:C210H315N57O57S
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