CAS 77500-04-0

MeIQx

Description:

MeIQx, or 2-amino-3-methylimidazo[4,5-f]quinoxaline, is a heterocyclic aromatic amine that is primarily formed during the cooking of meat at high temperatures, such as grilling or frying. It is classified as a mutagen and a potential carcinogen, which raises concerns regarding its presence in cooked foods. MeIQx is characterized by its complex structure, which includes a fused ring system that contributes to its chemical reactivity. The substance is soluble in organic solvents but has limited solubility in water. Its formation is influenced by various factors, including cooking time, temperature, and the type of meat. Due to its potential health risks, MeIQx has been the subject of numerous studies aimed at understanding its mechanisms of action and the extent of its occurrence in food products. Regulatory agencies monitor its levels in food to ensure consumer safety, and ongoing research continues to explore methods for reducing its formation during cooking processes.

Formula: C₁₁H₁₁N₅

InChI: InChI=1S/C11H11N5/c1-6-5-13-7-3-4-8-10(9(7)14-6)15-11(12)16(8)2/h3-5H,1-2H3,(H2,12,15)

InChI key: InChIKey=DVCCCQNKIYNAKB-UHFFFAOYSA-N

SMILES: CN1C2=C(C=3C(C=C2)=NC=C(C)N3)N=C1N

Synonyms:

• 2-Amino-3,8-dimethyl-3H-imidazo(4,5-f)quinoxaline
• 2-Amino-3,8-dimethylmidazo[4,5-f]quinoxaline
• 3,8-Dimethyl-3H-imidazo(4,5-f)quinoxalin-2-amine
• 3H-Imidazo(4,5-f)quinoxalin-2-amine, 3,8-dimethyl-
• 3H-Imidazo(4,5-f)quinoxaline, 2-amino-3,8-dimethyl-
• 8-MeIQX
• 8-Methyl-IQX
• Brn 4188271
• Ccris 2536
• Hsdb 7767
• MeIQx
• 2-Amino-3,8-dimethylimidazo(4,5-f)quinoxaline

2-Amino-3,8-dimethylimidazo(4,5-f)quinoxaline

CAS: 77500-04-0

Formula: C₁₁H₁₁N₅

Purity: 95%

Color and Shape: Solid

Molecular weight: 213.2385

Ref: IN-DA008OYJ

MeIQx

CAS: 77500-04-0

MeIQx, a carcinogenic compound in cooked fish/meat, triggers DNA-reactive metabolites and rat tumors.

Formula: C₁₁H₁₁N₅

Color and Shape: Solid

Molecular weight: 213.244

Ref: TM-T35681

2-Amino-3,8-dimethylimidazo[4,5-f]quinoxaline

CAS: 77500-04-0

2-Amino-3,8-dimethylimidazo[4,5-f]quinoxaline

Formula: C₁₁H₁₁N₅

Purity: ≥95%

Color and Shape: yellow to green solid

Molecular weight: 213.24g/mol

Ref: 54-OR0660T

2-Amino-3,8-dimethylimidazo[4,5-f]quinoxaline

Controlled Product

CAS: 77500-04-0

Stability Hygroscopic
Applications Mutagen found in white meat, increasing the rate of colorectal adenomas.
References Stavric, B., et al.: Fd. Chem. Toxic., 31, 12, 981 (1993), Sugimura, T., et al.: Mutation Research, 290, 43 (1993), Eisenbrand & Tang: Toxicology, 84, 1 (1993), Vikse, R., et al.: Mutation Research, 298, 207 (1993), Larsson, S., et al.: Int. J. Cancer, 119, 2657 (2006),

Formula: C₁₁H₁₁N₅

Color and Shape: Yellow To Green

Molecular weight: 213.24

Ref: TR-A606600

2-Amino-3,8-dimethylimidazo[4,5-f]quinoxaline

CAS: 77500-04-0

2-Amino-3,8-dimethylimidazo[4,5-f]quinoxaline is a reactive compound that has been shown to have anthelmintic properties. It is the most potent inhibitor of human cytochrome P450 3A4 (CYP3A4) and inhibits other enzymes such as dioxygenases and amidases. 2-Amino-3,8-dimethylimidazo[4,5-f]quinoxaline has been shown to have carcinogenic potential in rats and may be hazardous to humans at high doses; however, the levels of this compound found in humans are usually below those that would cause harm. The chemical structure of 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline has been studied by organic chemists who have used a variety of analytical techniques including electrochemical detection.

Formula: C₁₁H₁₁N₅

Purity: Min. 95%

Molecular weight: 213.24 g/mol

Ref: 3D-FA177581