CAS 77538-19-3

Glycerol behenate

Description:

Glycerol behenate, with the CAS number 77538-19-3, is a glycerol ester derived from behenic acid, a long-chain fatty acid. This compound is typically a white to off-white solid at room temperature and is known for its emulsifying and stabilizing properties, making it useful in various applications, particularly in the pharmaceutical and cosmetic industries. Glycerol behenate is often utilized as a surfactant and a thickening agent in formulations, enhancing the texture and stability of creams and lotions. Its hydrophobic nature allows it to form stable emulsions, while its glycerol backbone provides compatibility with both oil and water phases. Additionally, glycerol behenate is recognized for its biocompatibility and low toxicity, making it suitable for use in drug delivery systems and as an excipient in pharmaceutical formulations. Overall, glycerol behenate is valued for its multifunctional properties, contributing to the efficacy and stability of various products.

Formula: C₂₂H₄₄O₂·xC₃H₈O₃

InChI: InChI=1S/C22H44O2.C3H8O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22(23)24;4-1-3(6)2-5/h2-21H2,1H3,(H,23,24);3-6H,1-2H2

InChI key: InChIKey=BYNVYIUJKRRNNC-UHFFFAOYSA-N

SMILES: C(CCCCCCCCCCCCCC)CCCCCCC(O)=O.C(CO)(CO)O

Synonyms:

• 1,2,3-Propanetriol docosanoate
• 2,3-Dihydroxypropyl Docosanoate
• Behenin
• Compritol 888CG
• Compritol 888CG-ATO
• Docosanoin
• Glycerin behenate
• Glycerin docosanoate
• Glycerol behenate
• Glyceryl behenate
• Kolliwax GDB
• Poem B 200
• Rikemal B 200
• Speziol GDB
• Speziol GDB Pharma
• Sunsoft 8100CK

Glyceryl Behenate

Controlled Product

CAS: 77538-19-3

Applications Glyceryl Behenate is used as a carrier in lipid-based colloidal drug delivery system.
References Xu, Bin.: Zhongnan Yaoxue, 13(6), 619-623 (2015)

Formula: C₂₂H₄₄O₂·xC₃H₈O₃

Color and Shape: Neat

Molecular weight: 414.66

Ref: TR-G601470

Glyceryl behenate

CAS: 77538-19-3

Glyceryl behenate is a glycol ester that is used as an excipient in tablet formulations. It facilitates the absorption of drugs by increasing their solubility in water and may also increase the bioavailability of poorly soluble drugs. Glyceryl behenate is used as an absorption enhancer for cefpodoxime proxetil, which is a drug used to treat bacterial infections. This substance may also have therapeutic effects on alopecia areata, a disease characterized by hair loss. The thermodynamic data indicate that glyceryl behenate has low bioavailability due to its insolubility in aqueous media and its lack of affinity for lipid membranes.

Formula: C₂₅H₅₀O₄

Color and Shape: Powder

Molecular weight: 414.66 g/mol

Ref: 3D-FG145186