CAS 7759-35-5

Nestorone

Description:

Nestorone is a synthetic progestin, primarily used in hormonal contraceptives and hormone replacement therapies. It is characterized by its high potency and selectivity for progesterone receptors, which makes it effective in inhibiting ovulation and regulating menstrual cycles. Nestorone is known for its favorable pharmacokinetic profile, including a long half-life and the ability to be administered via various routes, such as oral, transdermal, or intramuscular. Its chemical structure allows it to mimic the natural hormone progesterone, leading to similar biological effects while minimizing androgenic activity. This selectivity is particularly beneficial in reducing side effects commonly associated with other progestins. Nestorone is also being researched for its potential applications in treating conditions like endometriosis and certain types of cancer. As with any hormonal agent, its use should be carefully monitored due to potential side effects and contraindications. Overall, Nestorone represents a significant advancement in the field of reproductive health and hormone therapy.

Formula: C₂₃H₃₀O₄

InChI: InChI=1S/C23H30O4/c1-13-11-21-20-7-5-16-12-17(26)6-8-18(16)19(20)9-10-22(21,4)23(13,14(2)24)27-15(3)25/h12,18-21H,1,5-11H2,2-4H3/t18-,19+,20+,21-,22-,23-/m0/s1

InChI key: InChIKey=CKFBRGLGTWAVLG-GOMYTPFNSA-N

SMILES: O(C(C)=O)[C@@]1(C(C)=O)[C@]2(C)[C@@](CC1=C)([C@]3([C@](CC2)([C@@]4(C(CC3)=CC(=O)CC4)[H])[H])[H])[H]

Synonyms:

• (17Alpha)-17-Acetyl-16-Methylidene-3-Oxoestr-4-En-17-Yl Acetate
• 16-Methylene-17α-acetoxy-19-nor-pregn-4-ene-3,20-dione
• 16-Methylene-17α-hydroxy-19-nor-4-pregnene-3,20-dione 17-acetate
• 17-(Acetyloxy)-16-methylene-19-norpregn-4-ene-3,20-dione
• 19-Norpregn-4-ene-3,20-dione, 17-(acetyloxy)-16-methylene-
• 19-Norpregn-4-ene-3,20-dione, 17-hydroxy-16-methylene-, acetate
• Elcometrine
• Nestorone
• Nestorone acetate
• Nestorone17-Hydroxy-16-methylene-19-norpregn-4-ene-3,20-dione acetate
• Segesterone acetate

Nestoron

CAS: 7759-35-5

Formula: C₂₃H₃₀O₄

Purity: 97%

Molecular weight: 370.4819

Ref: IN-DA00G2C9

Nestoron

CAS: 7759-35-5

Nestoron

Purity: ≥98%

Molecular weight: 370.48g/mol

Ref: 54-BUP10398

Nestorone (Segesterone Acetate)

CAS: 7759-35-5

Formula: C₂₃H₃₀O₄

Molecular weight: 370.49

Ref: 4Z-N-146001

Nestoron

CAS: 7759-35-5

Nestoron (Segesterone Acetate), a synthetic progestin, is a high-affinity agonist of the progesterone receptor (EC50: 10.3 nM).

Formula: C₂₃H₃₀O₄

Purity: 99.83% - 99.92%

Color and Shape: Solid

Molecular weight: 370.48

Ref: TM-T5174