CAS 77599-17-8

Panomifene

Description:

Panomifene, with the CAS number 77599-17-8, is a chemical compound that belongs to the class of selective estrogen receptor modulators (SERMs). It is primarily studied for its potential applications in the treatment of hormone-dependent conditions, particularly in breast cancer. Panomifene exhibits both estrogenic and anti-estrogenic properties, depending on the target tissue, which allows it to modulate estrogen receptor activity effectively. The compound is characterized by its ability to bind to estrogen receptors, influencing gene expression and cellular responses associated with estrogen signaling. Its pharmacological profile suggests that it may help in managing conditions related to estrogen imbalance. Additionally, Panomifene's chemical structure includes specific functional groups that contribute to its biological activity and interaction with estrogen receptors. As with many SERMs, the therapeutic use of Panomifene is accompanied by a consideration of potential side effects and the need for careful patient monitoring during treatment. Further research continues to explore its efficacy and safety in clinical settings.

Formula: C₂₅H₂₄F₃NO₂

InChI: InChI=1S/C25H24F3NO2/c26-25(27,28)24(21-9-5-2-6-10-21)23(19-7-3-1-4-8-19)20-11-13-22(14-12-20)31-18-16-29-15-17-30/h1-14,29-30H,15-18H2/b24-23+

InChI key: InChIKey=MHXVDXXARZCVRK-WCWDXBQESA-N

SMILES: C(=C(/C(F)(F)F)\C1=CC=CC=C1)(\C2=CC=C(OCCNCCO)C=C2)/C3=CC=CC=C3

Synonyms:

• (E)-1,2-Diphenyl-1-(4-((2-hydroxyethylamino)ethoxy)phenyl)-3,3,3-trifluoro-1-propene
• (E)-2-((2-(4-(3,3,3-Trifluoro-1,2-diphenyl-1-propenyl)phenoxy)ethyl)amino)ethanol
• (E)-2-((2-(p-(3,3,3-Trifluoro-1,2-diphenylpropenyl)phenoxy)ethyl)amino)ethanol
• 2-[(2-{4-[(1E)-3,3,3-trifluoro-1,2-diphenylprop-1-en-1-yl]phenoxy}ethyl)amino]ethanol
• 2-[[2-[4-[(1E)-3,3,3-Trifluoro-1,2-diphenyl-1-propen-1-yl]phenoxy]ethyl]amino]ethanol
• Egis 5660
• Ethanol, 2-((2-(4-(3,3,3-trifluoro-1,2-diphenyl-1-propenyl)phenoxy)ethyl)amino)-, (E)-
• Ethanol, 2-[[2-[4-[(1E)-3,3,3-trifluoro-1,2-diphenyl-1-propen-1-yl]phenoxy]ethyl]amino]-
• Ethanol, 2-[[2-[4-[(1E)-3,3,3-trifluoro-1,2-diphenyl-1-propenyl]phenoxy]ethyl]amino]-
• Gyki-13504
• Panomifene [INN]
• Panomifeno
• Panomifeno [Spanish]
• Panomifenum
• Panomifenum [Latin]

panomifene

CAS: 77599-17-8

Panomiphene (Gyki-13504, EGIS-5650) is an anti-estrogen drug that is a tamoxifen (TMX) analogue.

Formula: C₂₅H₂₄F₃NO₂

Color and Shape: Solid

Molecular weight: 427.46

Ref: TM-T33876

Panomifene

Controlled Product

CAS: 77599-17-8

Formula: C₂₅H₂₄F₃NO₂

Color and Shape: Neat

Molecular weight: 427.459

Ref: TR-P181000

Panomifene

CAS: 77599-17-8

Panomifene is an investigational pharmaceutical compound classified as an antiestrogen. It is synthesized in the laboratory, belonging to a class of selective estrogen receptor modulators (SERMs) that specifically binds to estrogen receptors. The mode of action of Panomifene involves the competitive inhibition of estrogen binding to its receptor sites, thereby modulating the transcription of estrogen-responsive genes. This blockade hampers estrogen-driven cellular proliferation, particularly in tissues such as breast tissue which are highly responsive to estrogen.

Formula: C₂₅H₂₄F₃NO₂

Purity: Min. 95%

Molecular weight: 427.5 g/mol

Ref: 3D-CDA59917