CAS 7761-45-7

Metoprine

Description:

Metoprine, with the CAS number 7761-45-7, is a chemical compound that belongs to the class of organic compounds known as piperidines. It is characterized by its molecular structure, which includes a piperidine ring and various functional groups that contribute to its chemical properties. Metoprine is primarily recognized for its role as a pharmaceutical agent, particularly in the context of its use as an antihistamine. It exhibits properties that allow it to interact with histamine receptors, thereby influencing allergic responses. The compound is typically a white to off-white solid and is soluble in organic solvents. Its stability and reactivity can vary depending on environmental conditions such as pH and temperature. As with many chemical substances, safety data sheets should be consulted for handling and toxicity information, as Metoprine may pose health risks if not managed properly. Overall, Metoprine's unique structure and properties make it significant in medicinal chemistry and pharmacology.

Formula: C₁₁H₁₀Cl₂N₄

InChI: InChI=1S/C11H10Cl2N4/c1-5-9(10(14)17-11(15)16-5)6-2-3-7(12)8(13)4-6/h2-4H,1H3,(H4,14,15,16,17)

InChI key: InChIKey=VQJHOPSWBGJHQS-UHFFFAOYSA-N

SMILES: CC=1C(=C(N)N=C(N)N1)C2=CC(Cl)=C(Cl)C=C2

Synonyms:

• 2,4-Diamino-5-(3',4'-dichlorophenyl)-6-methyl pyrimidine
• 2,4-Diamino-5-(3,4-dichlorophenyl)-6-methylpyrimidine
• 2,4-Pyrimidinediamine, 5-(3,4-dichlorophenyl)-6-methyl-
• 5-(3,4-Dichlorophenyl)-6-Methylpyrimidine-2,4-Diamine
• 5-(3,4-Dichlorophenyl)-6-methyl-2,4-pyrimidinediamine
• 5-(3,4-Dichlorphenyl)-6-methyl-2,4-pyrimidindiamin
• Ai3-26402
• Brn 0223622
• Bw 50-197
• Bw 50197
• Bw-197U
• Ddmp
• Methodichlorophen
• Metoprine [USAN]
• Nsc 19494
• Nsc 7364
• Pyrimidine, 2,4-diamino-5-(3,4-dichlorophenyl)-6-methyl-
• Sk 5265
• U 197
• Unii-2L9Rkx796Q

Metoprine

CAS: 7761-45-7

Metoprine

Purity: ≥98%

Molecular weight: 269.13g/mol

Ref: 54-BUP10931

Metoprine

CAS: 7761-45-7

Metoprine is a potent inhibitor of histamine N-methyltransferase (HMT), with potential antineoplastic activity.

Formula: C₁₁H₁₀Cl₂N₄

Purity: 98.42%

Color and Shape: Solid

Molecular weight: 269.13

Ref: TM-T8548

Metoprine

CAS: 7761-45-7

Stability Hygroscopic
Applications A 2,4-Diaminopyrimidine derivative as antimalarial agent.
References Andersson, K.J.I., et al.: Nature, 143, 720 (1939), Cecil, R., et al.: Biochem.J., et al.: 43, 592 (1948),

Formula: C₁₁H₁₀Cl₂N₄

Color and Shape: Neat

Molecular weight: 269.13

Ref: TR-M338835

Metoprine

CAS: 7761-45-7

Metoprine is a medication that is used to treat bowel diseases, including inflammatory bowel disease. Metoprine may be used in combination with other medications for the treatment of infectious diseases. It increases the production of thymidylate, which is an essential nucleotide for DNA synthesis and repair. This drug also has anti-cancer properties that have been demonstrated in animal models. Metoprine inhibits the growth of cancer cells by binding to epidermal growth factor receptor and blocking cellular proliferation. Metoprine has been shown to increase the glomerular filtration rate in rats as well as increase locomotor activity in mice.

Formula: C₁₁H₁₀Cl₂N₄

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 269.13 g/mol

Ref: 3D-FM25980