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CAS 77695-30-8

:

Sar-Pro-Arg-pNA

Description:
Sar-Pro-Arg-pNA, also known by its CAS number 77695-30-8, is a synthetic peptide substrate commonly used in biochemical research, particularly in studies involving proteases and enzyme kinetics. This compound consists of a sequence of amino acids, specifically sarcosine (Sar), proline (Pro), arginine (Arg), and is conjugated to p-nitroaniline (pNA), which serves as a chromogenic reporter. The presence of pNA allows for the quantification of enzymatic activity through colorimetric assays, as the cleavage of the peptide bond releases pNA, resulting in a measurable color change. Sar-Pro-Arg-pNA is characterized by its stability under physiological conditions, making it suitable for in vitro studies. Its specificity towards certain enzymes, particularly those that cleave at the arginine residue, makes it a valuable tool in the characterization of proteolytic activity. Overall, Sar-Pro-Arg-pNA is an important reagent in the field of enzymology and peptide research, facilitating the understanding of enzyme mechanisms and substrate specificity.
Formula:C20H30N8O5
Synonyms:
  • L-Argininamide, N-methylglycyl-L-prolyl-N-(4-nitrophenyl)-
  • Sar-PR-pNA
  • L-Argininamide, N-methylglycyl-L-prolyl-N-(4-nitrophenyl)- (9CI)
  • SAR-PRO-ARG-PNA
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Found 2 products.
  • Sar-Pro-Arg-pNA
    Bachem
    + Info

    Sar-Pro-Arg-pNA

    CAS:
    Chromogenic substrate for the assay of human α-thrombin. Km = 75 uM.
    Formula:C20H30N8O5
    Purity:97.0%
    Color and Shape:Whitish Powder
    Molecular weight:462.51

    Ref: 01-4027887

    50mg
    191.00€
    250mg
    729.00€
  • Sar-Pro-Arg-pNA hydrochloride salt
    Biosynth
    + Info

    Sar-Pro-Arg-pNA hydrochloride salt

    CAS:
    Sar-Pro-Arg-pNA (SPRAP) is a monoclonal antibody that is currently undergoing clinical trials for the treatment of diabetic patients. SPRAP binds to fibrinogen, an important protein in blood clotting, and inhibits the formation of clots. SPRAP has been shown to inhibit the growth of malignant melanoma cells. It also has an effect on cancer because it can induce apoptosis and cell cycle arrest. SPRAP inhibits protease activity, which can lead to tumor progression by inhibiting proteolytic cleavage of cell surface receptors. SPRAP also has a neutral ph and is stable at acidic pH levels.
    Formula:C20H30N8O5
    Purity:Min. 95%
    Molecular weight:462.5 g/mol

    Ref: 3D-FS110804

    100mg
    870.00€
    250mg
    1,144.00€
    500mg
    1,984.00€