CAS 777-11-7

Haloprogin

Description:

Haloprogin, with the CAS number 777-11-7, is an organic compound primarily recognized for its antifungal properties. It is a halogenated derivative of proguanil, which contributes to its effectiveness in inhibiting the growth of various fungi. Haloprogin is typically characterized by its white to off-white crystalline appearance and is soluble in organic solvents, while exhibiting limited solubility in water. The compound functions by disrupting the cellular processes of fungi, making it useful in treating fungal infections, particularly in dermatological applications. Its mechanism of action involves interference with nucleic acid synthesis, which is crucial for fungal cell replication. Haloprogin has been utilized in various formulations, including topical creams and solutions, and is known for its relatively low toxicity profile when used as directed. However, like many antifungal agents, it may cause skin irritation or allergic reactions in some individuals. As with any pharmaceutical agent, proper handling and adherence to safety guidelines are essential to minimize risks associated with its use.

Formula: C₉H₄Cl₃IO

InChI: InChI=1S/C9H4Cl3IO/c10-6-4-8(12)9(5-7(6)11)14-3-1-2-13/h4-5H,3H2

InChI key: InChIKey=CTETYYAZBPJBHE-UHFFFAOYSA-N

SMILES: O(CC#CI)C1=C(Cl)C=C(Cl)C(Cl)=C1

Synonyms:

• (3-Iod-2-propinyl)-(2,4,5-trichlorphenyl)ether
• 1,2,4-Trichloro-5-[(3-Iodoprop-2-Yn-1-Yl)Oxy]Benzene
• 1,2,4-Trichloro-5-[(3-iodo-2-propyn-1-yl)oxy]benzene
• 2,4,5-Trichlorophenyl gamma-iodopropargil ether
• 2,4,5-Trichlorophenyl iodopropargyl ether
• 2,4,5-Trichlorophenyl γ-iodopropargyl ether
• 2,4,5-Trichlorophenyl-gamma-iodopropargyl ether
• 3-Iodo-2-propynyl 2,4,5-trichlorophenyl ether
• Benzene, 1,2,4-trichloro-5-((3-iodo-2-propynyl)oxy)-
• Benzene, 1,2,4-trichloro-5-[(3-iodo-2-propyn-1-yl)oxy]-
• Brn 1976771
• Ether, 3-iodo-2-propynyl 2,4,5-trichlorophenyl
• Haloprogina
• Haloprogine
• Haloproginum
• Halotex
• M 1028
• M-1028 (Meiji)
• Mycanden
• Mycilan
• Nsc 100071
• Polik
• Unii-Aiu7053Owl

1,2,4-Trichloro-5-((3-iodoprop-2-yn-1-yl)oxy)benzene

CAS: 777-11-7

1,2,4-Trichloro-5-((3-iodoprop-2-yn-1-yl)oxy)benzene

Purity: 97%

Molecular weight: 361.39g/mol

Ref: 54-OR1056763

Haloprogin

Controlled Product

CAS: 777-11-7

Formula: C₉H₄Cl₃IO

Color and Shape: Neat

Molecular weight: 361.391

Ref: TR-H103780

Haloprogin-13C6

Controlled Product

CAS: 777-11-7

Formula: C₆C₃H₄Cl₃IO

Color and Shape: Neat

Molecular weight: 367.347

Ref: TR-H103782

Haloprogin

CAS: 777-11-7

Haloprogin is an antifungal agent with inhibitory activity against dermatophytes, Candida, and some Gram-positive bacteria.

Formula: C₉H₄Cl₃IO

Purity: 98.18%

Color and Shape: Solid

Molecular weight: 361.39

Ref: TM-T32042