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CAS 777-33-3

:

(S)-(-)-2-(trifluoroacetamido)succinic anhydride,

Description:
(S)-(-)-2-(trifluoroacetamido)succinic anhydride, with CAS number 777-33-3, is a chemical compound characterized by its anhydride functional group and the presence of a trifluoroacetamido substituent. This compound is typically a white to off-white solid at room temperature and is known for its reactivity, particularly in acylation reactions. The trifluoroacetamido group enhances its electrophilicity, making it useful in organic synthesis, especially in the modification of amino acids and peptides. The anhydride structure allows it to react with nucleophiles, facilitating the formation of amides or esters. Additionally, the presence of fluorine atoms contributes to its unique properties, such as increased lipophilicity and potential biological activity. Due to its specific stereochemistry, it may exhibit distinct interactions in biological systems, making it of interest in pharmaceutical research. Proper handling and storage are essential, as it may be sensitive to moisture and can react with water to form the corresponding acid.
Formula:C6H4F3NO4
InChI:InChI=1/C6H4F3NO4/c7-6(8,9)5(13)10-2-1-3(11)14-4(2)12/h2H,1H2,(H,10,13)/t2-/m0/s1
SMILES:C1[C@@H](C(=O)OC1=O)N=C(C(F)(F)F)O
Synonyms:
  • N-[(3S)-2,5-dioxotetrahydrofuran-3-yl]-2,2,2-trifluoroacetamide
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