CAS 77761-27-4

6-31-b-Endorphin (sheep),27-L-tyrosine-31-L-glutamic acid-

Description:

6-31-b-Endorphin (sheep), also known by its CAS number 77761-27-4, is a peptide that belongs to the class of endorphins, which are endogenous opioid neuropeptides. This substance is characterized by its role in modulating pain, stress, and emotional responses in the body. Structurally, it consists of a sequence of amino acids, including L-tyrosine and L-glutamic acid, which contribute to its biological activity. Endorphins like 6-31-b-Endorphin are produced in the central nervous system and pituitary gland and are known for their ability to bind to opioid receptors, leading to analgesic effects and feelings of euphoria. The specific sequence and modifications of this peptide can influence its potency and receptor selectivity. Additionally, it is important to note that the biological activity of endorphins can be affected by various factors, including receptor availability and the presence of other signaling molecules. Overall, 6-31-b-Endorphin plays a significant role in the body's natural pain relief and emotional regulation mechanisms.

Formula: C₁₃₁H₂₁₈N₃₄O₄₀

Synonyms:

• 6-31-b-Endorphin (human) (9CI)
• b-Endorphin (sheep),1-de-L-tyrosine-2-deglycine-3-deglycine-4-de-L-phenylalanine-5-de-L-methionine-27-L-tyrosine-31-L-glutamicacid-
• 6-31-b-Human endorphin
• 672: PN:US20090175821 SEQID: 831 claimed protein
• Human b-endorphin 6-31
• 166: PN: WO0069900 SEQID: 831 unclaimed sequence
• 6-31-β-Endorphin (human)
• beta-endorphin (6-31)
• b-Lipotropin (64-89) (huMan)
• H-Thr-Ser-Glu-Lys-Ser-Gln-Thr-Pro-Leu-Val-Thr-Leu-Phe-Lys-Asn-Ala-Ile-Ile-Lys-Asn-Ala-Tyr-Lys-Lys-Gly-Glu-OH

β-Endorphin (6-31) (human)

CAS: 77761-27-4

This β-endorphin fragment, in which the C-terminus is preserved, functions as a non-opioid β-endorphin antagonist and mediates effects on the immune system.

Formula: C₁₃₁H₂₁₈N₃₄O₄₀

Purity: >97%

Color and Shape: White

Molecular weight: 2909.38

Ref: 01-4030554

β-Endorphin (6-31), human

CAS: 77761-27-4

β-Endorphin is an endogenous opioid neuropeptide and opioid receptor agonist that preferentially binds to μ-opioid receptors.

Formula: C₁₃₁H₂₁₈N₃₄O₄₀

Purity: 98%

Color and Shape: Solid

Molecular weight: 2909.38

Ref: TM-T76285

β-Endorphin (6-31) (human)

CAS: 77761-27-4

Beta-endorphin (6-31) is a synthetic opiate that binds to the opioid receptor. This receptor is found in the brain, spinal cord, and gastrointestinal tract. Beta-endorphin (6-31) interacts with enkephalins, which are endogenous peptides that bind to the same receptor. These substances produce analgesia when they bind to the opioid receptors in the membranes of nerve cells. The analgesic effect of beta-endorphin (6-31) has been demonstrated using tail-flick tests in mice. In addition, beta-endorphin (6-31) has been shown to inhibit pain by acting on receptors located on brain membranes. Beta-endorphin (6-31) also exhibits enzymatic activity and can be used as a pentadecapeptide substrate for proteinases such as papain and trypsin.

Formula: C₁₃₁H₂₁₈N₃₄O₄₀

Purity: Min. 95%

Molecular weight: 2,909.34 g/mol

Ref: 3D-FE109157