CAS 778-16-5

1-[[4-(Trifluoromethyl)phenyl]methyl]cyclopropanamine

Description:

1-[[4-(Trifluoromethyl)phenyl]methyl]cyclopropanamine, identified by its CAS number 778-16-5, is a chemical compound characterized by its unique structure, which includes a cyclopropane ring and a trifluoromethyl-substituted phenyl group. This compound typically exhibits properties associated with amines, such as basicity and the ability to form hydrogen bonds. The presence of the trifluoromethyl group enhances its lipophilicity and can influence its reactivity and interaction with biological systems. The cyclopropane moiety contributes to the compound's rigidity, potentially affecting its conformational dynamics and steric interactions. Such structural features may render it useful in medicinal chemistry, particularly in the development of pharmaceuticals where specific interactions with biological targets are desired. Additionally, the trifluoromethyl group is known to impart unique electronic properties, which can be advantageous in various chemical reactions. Overall, this compound's characteristics make it a subject of interest in both synthetic and medicinal chemistry contexts.

Formula: C₁₁H₁₂F₃N

InChI: InChI=1S/C11H12F3N/c12-11(13,14)9-3-1-8(2-4-9)7-10(15)5-6-10/h1-4H,5-7,15H2

InChI key: InChIKey=NDTYOBBFEXGTHD-UHFFFAOYSA-N

SMILES: C(C1(N)CC1)C2=CC=C(C(F)(F)F)C=C2

Synonyms:

• 1-(4-(Trifluoromethyl)benzyl)cyclopropanamine
• Cyclopropanamine, 1-[[4-(trifluoromethyl)phenyl]methyl]-
• Cyclopropylamine, 1-[p-(trifluoromethyl)benzyl]-
• 1-(4-Trifluoromethylbenzyl)cyclopropylamine
• 1-[[4-(Trifluoromethyl)phenyl]methyl]cyclopropanamine