CAS 778-82-5

Ethyl 1H-indole-3-acetate

Description:

Ethyl 1H-indole-3-acetate, with the CAS number 778-82-5, is an organic compound that belongs to the class of indole derivatives. It features an indole ring, which is a bicyclic structure composed of a benzene ring fused to a pyrrole ring, and an acetate functional group attached to the nitrogen atom of the indole. This compound is typically a colorless to pale yellow liquid with a characteristic odor. Ethyl 1H-indole-3-acetate is known for its applications in the synthesis of various pharmaceuticals and agrochemicals, as well as its potential use in perfumery due to its pleasant fragrance. It is moderately soluble in organic solvents and exhibits low solubility in water. The compound is stable under normal conditions but should be handled with care, as it may pose health risks if ingested or inhaled. Its reactivity can be influenced by the presence of other functional groups and environmental conditions, making it a subject of interest in organic synthesis and medicinal chemistry.

Formula: C₁₂H₁₃NO₂

InChI: InChI=1S/C12H13NO2/c1-2-15-12(14)7-9-8-13-11-6-4-3-5-10(9)11/h3-6,8,13H,2,7H2,1H3

InChI key: InChIKey=HUDBDWIQSIGUDI-UHFFFAOYSA-N

SMILES: C(C(OCC)=O)C=1C=2C(NC1)=CC=CC2

Synonyms:

• (1H-Indol-3-yl)acetic acid ethyl ester
• 1H-indole-3-acetic acid, ethyl ester
• 3-[(Ethoxycarbonyl)methyl]indole
• Ethyl (1H-indol-3-yl)acetate
• Ethyl 1H-indol-3-ylacetate
• Ethyl 1H-indole-3-acetate
• Ethyl 2-(1H-indol-3-yl)acetate
• Ethyl 2-(indol-3-yl)acetate
• Ethyl indole-3-acetate
• Ethyl β-indolylacetate
• IAA ethyl ester
• Indole-3-acetic acid, ethyl ester

Ethyl indole-3-acetate, 98+%

CAS: 778-82-5

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₁₂H₁₃NO₂

Purity: 98+%

Color and Shape: White to cream to pale brown or pale yellow, Powder

Molecular weight: 203.24

Ref: 02-A13474

Ethyl 2-(1H-indol-3-yl)acetate

CAS: 778-82-5

Formula: C₁₂H₁₃NO₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 203.2371

Ref: IN-DA003Q17

Indole-3-acetic acid ethyl ester

CAS: 778-82-5

Formula: C₁₂H₁₃NO₂

Purity: ≥ 98.0%

Color and Shape: White to light yellow or pale-brown powder to crystals

Molecular weight: 203.24

Ref: 7W-GK1301

Ethyl 2-(1H-indol-3-yl)acetate

CAS: 778-82-5

Ethyl 2-(1H-indol-3-yl)acetate

Purity: 98%

Molecular weight: 203.24g/mol

Ref: 54-OR80296

Ethyl 3-Indoleacetate

CAS: 778-82-5

Formula: C₁₂H₁₃NO₂

Purity: >98.0%(GC)

Color and Shape: White to Light yellow to Light orange powder to crystal

Molecular weight: 203.24

Ref: 3B-E0878

Ethyl Indole-3-acetate

Controlled Product

CAS: 778-82-5

Applications Ethyl Indole-3-acetate is a compound used in the synthesis of 9H-Pyrrolo[1,2-α]Indoles via Michael Addition-Condensation with α,β-Unsaturated Ketimines.
References Zhang, M., et al.: J. Heterocyclic Chem. (2016)

Formula: C₁₂H₁₃NO₂

Color and Shape: Neat

Molecular weight: 203.24

Ref: TR-E919980

Indole-3-acetic acid ethyl ester

CAS: 778-82-5

Indole-3-acetic acid ethyl ester is a fine chemical that is used as a building block for synthesis of more complex compounds. It is a versatile building block that can be used in reactions to produce useful intermediates and scaffolds. Indole-3-acetic acid ethyl ester has been used to synthesize indole derivatives, which are useful in the research of cancer and Alzheimer's disease. Indole-3-acetic acid ethyl ester can also be used to produce indoles as well as other heterocyclic compounds, such as benzoxazines. The compound has CAS number 778-82-5.

Formula: C₁₂H₁₃NO₂

Purity: Min. 99.0 Area-%

Molecular weight: 203.24 g/mol

Ref: 3D-I-1100

Ethyl indole-3-acetate

CAS: 778-82-5

Ethyl indole-3-acetate (EIA) is a compound that inhibits the growth of certain cancer cells. It belongs to the group of acyl halides. EIA inhibits the synthesis of nucleic acids, proteins and other macromolecules by the cancer cells. It has been shown to be effective in reducing the size of tumors in mice with prostate and breast cancer. This compound also inhibits enzymes such as abscisic acid oxidase, which is responsible for converting abscisic acid into reactive oxygen species. EIA has been shown to have hemolytic activity in human lung tissue, but not ovules or human erythrocytes. This may be due to its ability to inhibit hormone production and cause an increase in progesterone levels.

Formula: C₁₂H₁₃NO₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 203.24 g/mol

Ref: 3D-FE10765

Ethyl 3-indoleacetate

CAS: 778-82-5

Formula: C₁₂H₁₃NO₂

Purity: 98%

Color and Shape: Solid, Crystalline

Molecular weight: 203.241

Ref: 10-F079500