CAS 77879-90-4

Gilvocarcin V

Description:

Gilvocarcin V is a natural product belonging to the class of anthracycline antibiotics, primarily derived from the fermentation of the bacterium Micromonospora. It exhibits a complex structure characterized by a tetracyclic ring system, which is typical of many anthracyclines. This compound is known for its potent antitumor activity, making it of interest in cancer research and potential therapeutic applications. Gilvocarcin V functions by intercalating into DNA, thereby disrupting the replication process and ultimately leading to cell death. Its mechanism of action is similar to that of other well-known chemotherapeutic agents, but it also possesses unique features that may contribute to its efficacy and specificity. Additionally, Gilvocarcin V has been studied for its ability to induce apoptosis in cancer cells, further highlighting its potential as a valuable agent in oncology. However, like many chemotherapeutics, it may also exhibit cytotoxic effects on normal cells, necessitating careful consideration in therapeutic contexts.

Formula: C₂₇H₂₆O₉

InChI: InChI=1/C27H26O9/c1-5-12-8-15-19(17(9-12)33-3)14-10-18(34-4)21-16(28)7-6-13(20(21)25(14)36-27(15)32)26-24(31)23(30)22(29)11(2)35-26/h5-11,22-24,26,28-31H,1H2,2-4H3/t11-,22+,23+,24-,26-/m1/s1

InChI key: InChIKey=XCWHINLKQMCRON-UCDARZNSSA-N

SMILES: O(C)C1=C2C(=C3C(C=4C(C(=O)O3)=CC(C=C)=CC4OC)=C1)C(=CC=C2O)[C@H]5O[C@@]([C@@H](C)O)([C@H](O)[C@H]5O)[H]

Synonyms:

• Antibiotic 1072B
• 6H-Benzo[d]naphtho[1,2-b]pyran-6-one, 4-(6-deoxy-α-D-galactofuranosyl)-8-ethenyl-1-hydroxy-10,12-dimethoxy-
• Gilvocarcin V
• NSC 338943
• 4-(6-Deoxy-α-D-galactofuranosyl)-8-ethenyl-1-hydroxy-10,12-dimethoxy-6H-benzo[d]naphtho[1,2-b]pyran-6-one
• AnandiMycin A, ToroMycin, 1072B
• 4-(6-Deoxy-alpha-D-galactofuranosyl)-8-ethenyl-1-hydroxy-10,12-dimethoxy-6H-benzo[d]naphtho[1,2-b]pyran-6-one
• Gilvocacin V
• NSC 348115
• 4-[(2R,3R,4R,5S)-3,4-dihydroxy-5-[(1R)-1-hydroxyethyl]oxolan-2-yl]-8-ethenyl-1-hydroxy-10,12-dimethoxynaphtho[1,2-c]isochromen-6-one
• DC-38-V

Gilvocarcin V

CAS: 77879-90-4

Gilvocarcin V, a metabolite from Actinomycete DO-38, exhibits potent antibacterial, antifungal, and antiviral activity.

Formula: C₂₇H₂₆O₆

Color and Shape: Solid

Molecular weight: 446.499

Ref: TM-TN7270

Gilvocarcin V

CAS: 77879-90-4

Formula: C₂₇H₂₆O₉

Purity: ≥ 98.0%

Color and Shape: Yellow solid or powder

Molecular weight: 494.5

Ref: 7W-GA3547