CAS 779-89-5

3-(Trifluoromethyl)cinnamic acid

Description:

3-(Trifluoromethyl)cinnamic acid is an organic compound characterized by its unique structure, which includes a trifluoromethyl group (-CF3) attached to the aromatic ring of a cinnamic acid derivative. This compound features a trans configuration, which is significant for its stability and reactivity. The presence of the trifluoromethyl group enhances the lipophilicity and alters the electronic properties of the molecule, making it a valuable intermediate in organic synthesis and medicinal chemistry. It typically appears as a white to off-white solid and is sparingly soluble in water but more soluble in organic solvents. The compound exhibits interesting properties such as potential antimicrobial and anti-inflammatory activities, making it a subject of research in pharmaceutical applications. Additionally, its unique fluorinated structure can influence its behavior in various chemical reactions, including electrophilic aromatic substitution and cross-coupling reactions. Safety data indicates that, like many fluorinated compounds, it should be handled with care due to potential toxicity and environmental concerns.

Formula: C₁₀H₇F₃O₂

InChI: InChI=1S/C10H7F3O2/c11-10(12,13)8-3-1-2-7(6-8)4-5-9(14)15/h1-6H,(H,14,15)

InChI key: InChIKey=KSBWHDDGWSYETA-UHFFFAOYSA-N

SMILES: C(F)(F)(F)C1=CC(C=CC(O)=O)=CC=C1

Synonyms:

• (2E)-3-[3-(trifluoromethyl)phenyl]prop-2-enoate
• 2-Propenoic acid, 3-[3-(trifluoromethyl)phenyl]-
• 3-(3-Trifluoromethylphenyl)acrylic acid
• 3-(Trifluormethyl) cinnamic acid
• 3-[3-(Trifluoromethyl)phenyl]-2-propenoic acid
• Cinnamic acid, m-(trifluoromethyl)-
• m-(Trifluoromethyl)cinnamic acid
• 3-(Trifluoromethyl)cinnamic acid

3-(Trifluoromethyl)cinnamic Acid

CAS: 779-89-5

Formula: C₁₀H₇F₃O₂

Purity: >99.0%(GC)(T)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 216.16

Ref: 3B-T1547

3-(Trifluoromethyl)cinnamic acid, predominantly trans, 98+%

CAS: 779-89-5

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₁₀H₆F₃O₂

Purity: 98+%

Color and Shape: White to pale cream, Crystals or powder or crystalline powder

Molecular weight: 215.15

Ref: 02-A16983

3-(Trifluoromethyl)cinnamic acid, predominantly trans

CAS: 779-89-5

Formula: C₁₀H₇F₃O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 216.1566

Ref: IN-DA003IAV

3-(Trifluoromethyl)cinnamic acid

CAS: 779-89-5

3-(Trifluoromethyl)cinnamic acid

Formula: C₁₀H₇F₃O₂

Purity: 98%

Color and Shape: white solid

Molecular weight: 216.16g/mol

Ref: 54-PC7663

3-Trifluoromethylcinnamic acid

CAS: 779-89-5

Formula: C₁₀H₇F₃O₂

Molecular weight: 216.16

Ref: 7W-GK0499

3-(Trifluoromethyl)cinnamic acid

CAS: 779-89-5

3-(Trifluoromethyl)cinnamic acid

Purity: ≥98%

Molecular weight: 216.157g/mol

Ref: 54-BUP13888

3-(Trifluoromethyl)cinnamic Acid

Controlled Product

CAS: 779-89-5

Formula: C₁₀H₇F₃O₂

Color and Shape: Neat

Molecular weight: 216.16

Ref: 86-MM3370.03

3-(Trifluoromethyl)cinnamic acid

CAS: 779-89-5

3-(Trifluoromethyl)cinnamic acid (3-(3-(Trifluoromethyl)phenyl)acrylic acid) can be used to study drug-resistant bacterial infections.

Formula: C₁₀H₇F₃O₂

Purity: 99.59%

Color and Shape: Solid

Molecular weight: 216.157

Ref: TM-T64860

3-(Trifluoromethyl)cinnamic acid

CAS: 779-89-5

Formula: C₁₀H₇F₃O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 216.159

Ref: 10-F007614

3-(Trifluoromethyl)cinnamic acid

CAS: 779-89-5

3-(Trifluoromethyl)cinnamic acid (3TCA) is a cinnamic acid derivative that has been synthesized and studied. It is a supramolecular chemistry that has been shown to inhibit the activity of dehydrogenases, which are enzymes involved in postprandial plasma glucose metabolism. 3TCA is also a peptidomimetic and can be used as an inhibitor for cancer cells. 3TCA binds to the active site of dehydrogenases, blocking the transfer of electrons from NADH to coenzyme A and disrupting electron transport. This inhibition leads to decreased levels of acetyl-CoA and ATP, resulting in cell death. 3TCA has also been found to be useful as an inhibitor for amide hydrolase, which is an enzyme involved in the breakdown of proteins into amino acids. 3TCA can be used in techniques such as molecular modeling, crystal x-ray diffraction, and clinical use.

Formula: C₁₀H₇F₃O₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 216.16 g/mol

Ref: 3D-FT64231