CAS 7791-71-1

5'-O-tritylthymidine

Description:

5'-O-Tritylthymidine is a modified nucleoside that features a thymidine base with a trityl protecting group at the 5' hydroxyl position. This compound is characterized by its structural components, which include a pyrimidine base (thymine) linked to a deoxyribose sugar. The trityl group, a bulky aromatic hydrocarbon moiety, serves to protect the hydroxyl group from unwanted reactions during synthetic processes, making it valuable in nucleic acid chemistry, particularly in the synthesis of oligonucleotides. The presence of the trityl group enhances the compound's stability and solubility in organic solvents. 5'-O-Tritylthymidine is typically used in biochemical applications, including DNA synthesis and modification, where selective deprotection is required to facilitate further reactions. Its CAS number, 7791-71-1, is a unique identifier that allows for easy reference in chemical databases. Overall, this compound plays a crucial role in the field of molecular biology and synthetic chemistry, enabling researchers to manipulate nucleic acids with precision.

Formula: C₂₉H₂₈N₂O₅

InChI: InChI=1/C29H28N2O5/c1-20-18-31(28(34)30-27(20)33)26-17-24(32)25(36-26)19-35-29(21-11-5-2-6-12-21,22-13-7-3-8-14-22)23-15-9-4-10-16-23/h2-16,18,24-26,32H,17,19H2,1H3,(H,30,33,34)

SMILES: Cc1cn(C2CC(C(COC(c3ccccc3)(c3ccccc3)c3ccccc3)O2)O)c(=O)nc1O

Synonyms:

• Thymidine, 5'-O-(triphenylmethyl)-
• 1-(2-deoxy-5-O-tritylpentofuranosyl)-5-methylpyrimidine-2,4(1H,3H)-dione

5'-O-Tritylthymidine

CAS: 7791-71-1

Formula: C₂₉H₂₈N₂O₅

Purity: 97%

Color and Shape: Solid

Molecular weight: 484.5430

Ref: IN-DA005QN3

1-((2R,4S,5R)-4-Hydroxy-5-((Trityloxy)Methyl)Tetrahydrofuran-2-Yl)-5-Methylpyrimidine-2,4(1H,3H)-Dione

CAS: 7791-71-1

1-((2R,4S,5R)-4-Hydroxy-5-((Trityloxy)Methyl)Tetrahydrofuran-2-Yl)-5-Methylpyrimidine-2,4(1H,3H)-Dione

Purity: 98%

Molecular weight: 484.55g/mol

Ref: 54-OR1030384

5''-O-Tritylthymidine

CAS: 7791-71-1

Formula: C₂₉H₂₈N₂O₅

Molecular weight: 484.54

Ref: 7W-GN2546

5'-O-Tritylthymidine

CAS: 7791-71-1

Color and Shape: Neat

Ref: 86-MM0173.11

5'-O-Tritylthymidine

CAS: 7791-71-1

5'-O-Tritylthymidine is a nucleoside that is found in human mitochondrial DNA. It is synthesized from uridine by the enzyme thymidylate synthase and can be converted to thymine by the enzyme thymidine phosphorylase. 5'-O-Tritylthymidine has been shown to inhibit cancer cell growth, but its mechanism of action is not clear. It may inhibit xylene production. 5'-O-Tritylthymidine also causes an increase in p53 activity, which may lead to apoptosis of cancer cells.

Formula: C₂₉H₂₈N₂O₅

Purity: Min. 95%

Molecular weight: 484.54 g/mol

Ref: 3D-NT08062

5′-O-Tritylthymidine

CAS: 7791-71-1

Formula: C₂₉H₂₈N₂O₅

Purity: 97%,contains <10%DCM)

Color and Shape: Liquid

Molecular weight: 484.552

Ref: 10-F361945

5'-O-Tritylthymidine

CAS: 7791-71-1

5'-O-Tritylthymidine blocks FAK/Mdm-2, activates p53 & caspase-8, promoting apoptosis in breast/colon cancer.

Formula: C₂₉H₂₈N₂O₅

Color and Shape: Solid

Molecular weight: 484.54

Ref: TM-T19906