CAS 77928-70-2

N-[3-({4-[(3-aminopropyl)amino]butyl}amino)propyl]acetamide

Description:

N-[3-({4-[(3-aminopropyl)amino]butyl}amino)propyl]acetamide, with the CAS number 77928-70-2, is a synthetic organic compound characterized by its complex structure, which includes multiple amine functional groups. This compound typically exhibits properties associated with amines, such as being hygroscopic and soluble in water due to the presence of polar functional groups. It may act as a ligand in coordination chemistry or as a building block in the synthesis of more complex molecules. The presence of both acetamide and multiple amino groups suggests potential applications in pharmaceuticals, particularly in drug design, where it may serve as a scaffold for biologically active compounds. Additionally, its structure may confer specific biological activities, making it of interest in medicinal chemistry. Safety data and handling precautions should be considered, as compounds with amine functionalities can be reactive and may pose health risks if not managed properly.

Formula: C₁₂H₃₁Cl₃N₄O

InChI: InChI=1/C12H28N4O/c1-12(17)16-11-5-10-15-8-3-2-7-14-9-4-6-13/h14-15H,2-11,13H2,1H3,(H,16,17)

SMILES: CC(=NCCCNCCCCNCCCN)O

Synonyms:

• acetamide, N-[3-[[4-[(3-aminopropyl)amino]butyl]amino]propyl]-
• N-[3-({4-[(3-Aminopropyl)amino]butyl}amino)propyl]acetamid
• N-[3-({4-[(3-Aminopropyl)amino]butyl}amino)propyl]acétamide
• N-(3-((4-((3-aminopropyl)amino)butyl)amino)propyl)-Acetamide
• N-(3-((4-((3-aminopropyl)amino)butyl)amino)propyl)acetamide trihydrochloride
• N1-ACETYLSPERMINE TRIHYDROCHLORIDE
• N1-Acetylspermine (hydrochloride)
• 1-ACETYLSPERMINE TRIHYDROCHLORIDE

N1-Acetylspermine trihydrochloride

CAS: 77928-70-2

N1-Acetylspermine trihydrochloride: monoacetylated spermine, aids in bleomycin-A5 uptake studies via SLC22A16.

Formula: C₁₂H₃₁Cl₃N₄O

Purity: 98.79% - 99.93%

Color and Shape: Solid

Molecular weight: 353.76

Ref: TM-T36416

N¹-Acetylspermine trihydrochloride

CAS: 77928-70-2

Formula: C₁₂H₃₁Cl₃N₄O

Purity: 97.0%

Color and Shape: Solid

Molecular weight: 353.7597

Ref: IN-DA00GGVE

N1-Acetylspermine trihydrochloride

CAS: 77928-70-2

N1-Acetylspermine trihydrochloride

Purity: ≥98%

Molecular weight: 353.76g/mol

Ref: 54-BUP13860

Acetylspermine TriHCl

CAS: 77928-70-2

Formula: C₁₂H₂₈N₄O·3HCl

Molecular weight: 244.38 3*36.46

Ref: 4Z-A-429001

N1-Acetylspermine Trihydrochloride

Controlled Product

CAS: 77928-70-2

Applications N1-Acetylspermine Trihydrochloride is a monoacetylated derivative of Spermine (S680510); a biogenic polyamine formed from Spermidine (S680400) that occurs in almost all tissues. Spermine is also essential for both normal and neoplastic tissue growth and is involved in the modulation of calcium-dependent immune processes.
References Israel, et al.: J. Med. Chem., 7, 710 (1964); Janne, J., et al.: Biochim. Biophys. Acta, 473, 241 (1978); Theoharides, T.C., et al.: Life Sci., 27, 703 (1980); Horn, Y., et al.: Cancer Res., 42, 3248 (1982)

Formula: C₁₂H₃₁Cl₃N₄O

Color and Shape: Neat

Molecular weight: 353.76

Ref: TR-A188005

N1-Acetylspermine-d3 Trihydrochloride

Controlled Product

CAS: 77928-70-2

Applications N1-Acetylspermine-d3 Trihydrochloride is the isotope labelled analog of N1-Acetylspermine Trihydrochloride (A188005); a monoacetylated derivative of Spermine (S680510) which is a biogenic polyamine formed from Spermidine (S680400) that occurs in almost all tissues. Spermine is also essential for both normal and neoplastic tissue growth and is involved in the modulation of calcium-dependent immune processes.
References Israel, et al.: J. Med. Chem., 7, 710 (1964); Janne, J., et al.: Biochim. Biophys. Acta, 473, 241 (1978); Theoharides, T.C., et al.: Life Sci., 27, 703 (1980); Horn, Y., et al.: Cancer Res., 42, 3248 (1982)

Formula: C₁₂H₂₈D₃Cl₃N₄O

Color and Shape: Neat

Molecular weight: 356.78

Ref: TR-A188007

N¹-Acetylspermine Trihydrochloride

CAS: 77928-70-2

N-Acetylspermine trihydrochloride is a metabolic agent that is used in the treatment of solid phase microextraction. It has been shown to inhibit the activities of various enzymes, such as aminopeptidase and alkaline phosphatase, and to have a protective effect on human serum. N-Acetylspermine trihydrochloride also has a protective effect on bowel disease induced by inflammatory agents. It has been shown to be an effective therapeutic agent for some types of bowel disease, including ulcerative colitis and Crohn's disease. N-Acetylspermine-d3 trihydrochloride is absorbed from the gut into the bloodstream and then metabolized by liver enzymes before being excreted in urine.

Formula: C₁₂H₂₈N₄O•3HCl

Purity: Min. 95%

Molecular weight: 353.76 g/mol

Ref: 3D-CDA92870