CAS 78-98-8

Methylglyoxal

Description:

Methylglyoxal, with the CAS number 78-98-8, is a simple α-oxoaldehyde characterized by its chemical formula C3H4O2. It is a colorless to pale yellow liquid with a sweet, slightly pungent odor. Methylglyoxal is highly soluble in water and exhibits hygroscopic properties, meaning it can absorb moisture from the air. This compound is known for its reactivity, particularly in forming adducts with amino acids and proteins, which can lead to the formation of advanced glycation end-products (AGEs). Methylglyoxal is produced naturally in small amounts during glycolysis and is also found in various food products, particularly in roasted coffee and certain types of honey. It has garnered attention for its potential biological effects, including antimicrobial properties and implications in diabetes-related complications. However, it is also recognized for its cytotoxicity at higher concentrations. Due to its reactivity and biological significance, methylglyoxal is of interest in both research and industrial applications, particularly in the fields of biochemistry and food science.

Formula: C₃H₄O₂

InChI: InChI=1S/C3H4O2/c1-3(5)2-4/h2H,1H3

InChI key: InChIKey=AIJULSRZWUXGPQ-UHFFFAOYSA-N

SMILES: C(C=O)(C)=O

Synonyms:

• 2-Ketopropionaldehyde
• 2-Oxopropanal
• 2-Oxopropionaldehyde
• Acetylaldehyde
• Acetylformaldehyde
• Acetylformyl
• Methylglyoxal
• Nsc 626580
• Nsc 79019
• Piruvaldehido
• Pyroracemic aldehyde
• Pyruvaldehyd
• Pyruvaldehyde
• Pyruvic aldehyde
• α-Ketopropionaldehyde

Pyruvic aldehyde, 35-45% w/w aq. soln

CAS: 78-98-8

Pyruvic aldehyde is used in the synthesis and cytotoxicity evaluation of N-terminal analogues of tubulysin-U an antimitotic compound. Also used in the synthesis of imidazoles as potent calcitonin gene-related CGRP antagonists. This Thermo Scientific Chemicals brand product was originally part of the

Formula: C₃H₄O₂

Color and Shape: Clear colorless to yellow to orange, Liquid

Molecular weight: 72.06

Ref: 02-B24664

2-oxopropanal, 40% in water

CAS: 78-98-8

Formula: C₃H₄O₂

Purity: .%

Color and Shape: Liquid

Molecular weight: 72.0627

Ref: IN-DA0035K2

Pyruvaldehyde, 40% aqueous solution

CAS: 78-98-8

Pyruvaldehyde, 40% aqueous solution

Formula: C₃H₄O₂

Purity: ≥95%

Color and Shape: clear. yellow to dark yellow liquid

Molecular weight: 72.06g/mol

Ref: 54-OR5752

Pyruvic aldehyde

CAS: 78-98-8

Pyruvic aldehyde

Purity: ≥95%

Molecular weight: 72.06g/mol

Ref: 54-BUP18022

Methylglyoxal solution 40% in water

CAS: 78-98-8

Formula: C₃H₄O₂

Color and Shape: Clear, yellow to brown liquid

Molecular weight: 72.06

Ref: 7W-GL9346

Pyruvaldehyde, 35% aqueous solution

CAS: 78-98-8

Pyruvaldehyde, 35% aqueous solution

Formula: C₃H₄O₂

Purity: ≥95%

Color and Shape: clear. yellow liquid

Molecular weight: 72.06g/mol

Ref: 54-OR53061

EPA Method 556 Carbonyl Mixture 457 1000 µg/mL in Acetonitrile

Controlled Product

CAS: 100-52-7, 107-22-2, 108-94-1, 110-62-3, 111-71-7, 112-31-2, 123-38-6, 123-72-8, 123-73-9, 124-13-0, 124-19-6, 50-00-0, 66-25-1, 75-07-0, 78-98-8

Color and Shape: Mixture

Ref: 04-A50000457AL

Pyruvic aldehyde

CAS: 78-98-8

Pyruvic aldehyde is a flavoring agent, and in tanning.

Formula: C₃H₄O₂

Purity: 98%

Color and Shape: Clear Yellow Liquid Vapors Faintly Acidic To Litmus (Ntp 1992)

Molecular weight: 72.06

Ref: TM-T19536

Pyruvic aldehyde - Technical grade, 35-45% w/w aqueous solution

CAS: 78-98-8

Pyruvic aldehyde is a reactive compound that is an intermediate in the glycolytic pathway. It is used in vitro to measure enzyme activities and as a model system for studying pathogenic mechanisms. Pyruvic aldehyde has been shown to damage mitochondrial membranes by increasing the production of reactive oxygen species, leading to the collapse of mitochondrial membrane potential and cell death. The methylglyoxal-derived compound also has pharmacological effects, such as anti-inflammatory activities. Pyruvic aldehyde can be prepared using preparative high-performance liquid chromatography (Hplc) or by reacting pyruvate with acidified ethyl acetate.

Formula: C₃H₄O₂

Color and Shape: Brown Yellow Clear Liquid

Molecular weight: 72.06 g/mol

Ref: 3D-FP33211

Pyruvic Aldehyde (40% in water)

CAS: 78-98-8

Formula: C₃H₄O₂

Purity: 98.0%

Color and Shape: Liquid

Molecular weight: 72.063

Ref: 10-F069255

Pyruvaldehyde (35% w/w aqueous)

Controlled Product

CAS: 78-98-8

Applications Pyruvaldehyde is used in the synthesis and cytotoxicity evaluation of N-terminal analogues of tubulysin-U an antimitotic compound. Also used in the synthesis of imidazoles as potent calcitonin gene-related CGRP antagonists.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Shankar, S. et al.: Tetrahedron Lett., 54, 6137 (2013); Tora, G. et al.: Bioorg. Med. Chem. Lett., 23, 5684 (2013);

Formula: C₃H₄O₂

Color and Shape: Neat

Molecular weight: 72.06

Ref: TR-P998870