CAS 78033-08-6

8-Methoxymethyl-3-isobutyl-1-methylxanthine

Description:

8-Methoxymethyl-3-isobutyl-1-methylxanthine, identified by its CAS number 78033-08-6, is a synthetic compound belonging to the xanthine class of molecules, which are known for their role as stimulants and phosphodiesterase inhibitors. This compound features a complex structure characterized by a xanthine core, which is modified with methoxymethyl and isobutyl groups, contributing to its unique pharmacological properties. It is typically studied for its potential effects on the central nervous system and its ability to enhance cognitive function. The presence of the methoxymethyl group may influence its solubility and bioavailability, while the isobutyl group can affect its interaction with biological targets. As a xanthine derivative, it may exhibit properties similar to caffeine and theophylline, including vasodilation and increased heart rate. However, specific biological activities, therapeutic applications, and safety profiles would require further investigation through empirical studies. Overall, this compound represents a fascinating area of research within medicinal chemistry and pharmacology.

Formula: C₁₂H₁₈N₄O₃

InChI: InChI=1S/C12H18N4O3/c1-7(2)5-16-10-9(11(17)15(3)12(16)18)13-8(14-10)6-19-4/h7H,5-6H2,1-4H3,(H,13,14)

InChI key: InChIKey=NBLBCGUCPBXKOV-UHFFFAOYSA-N

SMILES: C(C(C)C)N1C2=C(NC(COC)=N2)C(=O)N(C)C1=O

Synonyms:

• 1-Methyl-3-isobutyl-8-methoxymethylxanthine
• 1H-Purine-2,6-dione, 3,7-dihydro-8-(methoxymethyl)-1-methyl-3-(2-methylpropyl)-
• 1H-Purine-2,6-dione, 3,9-dihydro-8-(methoxymethyl)-1-methyl-3-(2-methylpropyl)-
• 3,9-Dihydro-8-(methoxymethyl)-1-methyl-3-(2-methylpropyl)-1H-purine-2,6-dione
• 3-Isobutyl-8-(methoxymethyl)-1-methyl-1H-purine-2,6(3H,7H)-dione
• 8-(Methoxymethyl)-1-methyl-3-(2-methylpropy l)-7H-purine-2,6-dione
• 8-(methoxymethyl)-1-methyl-3-(2-methylpropyl)-3,7-dihydro-1H-purine-2,6-dione
• 8-Methoxymethyl-3-isobutyryl-1-methylxanthine
• 8-Methoxymethyl-3-isobutyl-1-methylxanthine

8-Methoxymethyl-isobutyryl-1-methylxanthine

CAS: 78033-08-6

Formula: C₁₂H₁₈N₄O₃

Color and Shape: Solid

Molecular weight: 266.2963

Ref: IN-DA003JLY

8-Methoxymethyl-3-isobutyl-1-methylxanthine

CAS: 78033-08-6

Formula: C₁₂H₁₈N₄O₃

Molecular weight: 266.30

Ref: 7W-GL8233

8-Methoxymethyl-1-methyl-3-(2-methylpropyl) Xanthine

Controlled Product

CAS: 78033-08-6

Applications A specific inhibitor of calmodulin-sensitive cyclic GMP phosphodiesterase. Selective PDE1 inhibitor.
References Ahlstroem, M., Cell. Mol. Biol. Lett., 10, 305 (2005), Marte, A., et al.: J. Neurosci. Res., 86, 3338 (2008),

Formula: C₁₂H₁₈N₄O₃

Color and Shape: Neat

Molecular weight: 266.30

Ref: TR-M264500

8-Methoxymethyl-1-methyl-3-(2-methylpropyl) xanthine

Controlled Product

CAS: 78033-08-6

8-Methoxymethyl-1-methyl-3-(2-methylpropyl) xanthine (8MMX) is an intracellular calcium ion chelator that inhibits enzyme activity in the cyclic nucleotide phosphodiesterase enzyme family. 8MMX has been shown to be a potent inhibitor of both cyclic nucleotide phosphodiesterases and cyclic nucleotide phosphodiesterase isoenzymes. 8MMX has been shown to inhibit bladder contractility and improve bladder function in animal models. It also reduces the incidence of papillary muscle rupture, which can lead to heart failure, and improves ventricular function by increasing the rate of relaxation of the left ventricle.
8MMX is a potential treatment for pulmonary hypertension, which is caused by increased concentrations of intracellular calcium ions.

Formula: C₁₂H₁₈N₄O₃

Purity: Min. 95%

Molecular weight: 266.3 g/mol

Ref: 3D-FM25310

MMPX

CAS: 78033-08-6

calmodulin-sensitive cyclic GMP phosphodiesterase inhibitor

Formula: C₁₂H₁₈N₄O₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 266.3

Ref: TM-T23009