CAS 78081-87-5

N(alpha),N(epsilon)-di-fmoc-L-lysine

Description:

N(alpha),N(epsilon)-di-fmoc-L-lysine is a protected form of the amino acid lysine, commonly used in peptide synthesis and bioconjugation. The "fmoc" (9-fluorenylmethoxycarbonyl) groups serve as protective groups for the amino functionalities, allowing for selective reactions without interfering with the lysine's reactivity. This compound features two fmoc groups, one on the alpha amino group and another on the epsilon amino group of lysine, which enhances its stability and solubility in organic solvents. The presence of these protective groups facilitates the synthesis of peptides by preventing unwanted side reactions during the coupling process. Additionally, N(alpha),N(epsilon)-di-fmoc-L-lysine can be deprotected under mild basic conditions, allowing for the release of the free amino groups when needed. Its structural characteristics contribute to its utility in the development of various biopharmaceuticals and research applications in peptide chemistry. Overall, this compound is valued for its versatility and effectiveness in facilitating the synthesis of complex peptide structures.

Formula: C₃₆H₃₄N₂O₆

InChI: InChI=1/C36H34N2O6/c39-34(40)33(38-36(42)44-22-32-29-17-7-3-13-25(29)26-14-4-8-18-30(26)32)19-9-10-20-37-35(41)43-21-31-27-15-5-1-11-23(27)24-12-2-6-16-28(24)31/h1-8,11-18,31-33H,9-10,19-22H2,(H,37,41)(H,38,42)(H,39,40)/t33-/m0/s1

SMILES: c1ccc2c(c1)c1ccccc1C2COC(=NCCCC[C@@H](C(=O)O)N=C(O)OCC1c2ccccc2c2ccccc12)O

Synonyms:

• Fmoc-Lys(Fmoc)-OH
• N2,N6-bis[(9H-fluoren-9-ylmethoxy)carbonyl]-L-lysine
• N2,N6-Bis-Fmoc-L-lysine

Nα,Nε-Bis[(9H-fluoren-9-ylmethoxy)carbonyl]-L-lysine

CAS: 78081-87-5

Formula: C₃₆H₃₄N₂O₆

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 590.68

Ref: 3B-B4931

Fmoc-Lys(Fmoc)-OH

CAS: 78081-87-5

Building block for the synthesis of branched peptides and MAP matrices.

Formula: C₃₆H₃₄N₂O₆

Purity: 98.8%

Color and Shape: White

Molecular weight: 590.68

Ref: 01-4011122

Fmoc-Lys(Fmoc)-OH

CAS: 78081-87-5

Formula: C₃₆H₃₄N₂O₆

Purity: 97%

Color and Shape: Solid

Molecular weight: 590.6650

Ref: IN-DA00ICX5

Fmoc-Lys(Fmoc)-OH

CAS: 78081-87-5

Fmoc-Lys(Fmoc)-OH

Purity: 98%

Molecular weight: 590.66g/mol

Ref: 54-OR1013374

Fmoc-Lys(Fmoc)-OH

CAS: 78081-87-5

Purity: ≥ 98.0%

Color and Shape: White to faint yellow or beige powder

Molecular weight: 590.66

Ref: 7W-GM2885

fmoc-lys(fmoc)-oh

CAS: 78081-87-5

Formula: C₃₆H₃₄N₂O₆

Purity: 95%

Color and Shape: Solid

Molecular weight: 590.676

Ref: 10-F045471

Fmoc-Lys(Fmoc)-OH

CAS: 78081-87-5

Fmoc-Lys(Fmoc)-OH is an ester of lysine that is used in peptide synthesis. It has shown to have antimicrobial properties against bacteria and fungi. Fmoc-Lys(Fmoc)-OH has been found to be taken up by cancer cells, suggesting that it may have anticancer effects. It has also been found to inhibit the growth of bladder cancer cells as well as histidine aminopeptidase from the cell surface. Fmoc-Lys(Fmoc)-OH is stable in trifluoroacetic acid, making it a good candidate for solid-phase synthesis. This product can be synthesized by attaching the amino acid lysine to an ester linker with a fluorinated side chain. The product is then linked end-to-end via intramolecular hydrogen bonds and chemical stability is achieved through covalent amide bond formation between Lys and Fmoc groups

Formula: C₃₆H₃₄N₂O₆

Purity: Min. 95%

Color and Shape: Solid

Molecular weight: 590.67 g/mol

Ref: 3D-FF28934

Fmoc-Lys(Fmoc)-OH

CAS: 78081-87-5

Fmoc-Lys(Fmoc)-OH is an antibacterial agent that can be synthesized from a number of precursors. It has been shown to inhibit the uptake of mannose by staphylococcus cells and its subsequent use in the synthesis of bacterial cell walls. Fmoc-Lys(Fmoc)-OH also inhibits the growth of viruses, such as HIV, and human immunodeficiency virus type 1 (HIV-1), by binding to mannose receptors on the surface of macrophage-like cells. Intramolecular hydrogen bonds stabilise this complex, which prevents it from breaking down. This allows Fmoc-Lys(Fmoc)-OH to remain in the body for a longer period of time than other antibiotics that are broken down by enzymes. Fmoc-Lys(Fmoc)-OH has also been shown to be an effective antibacterial agent against Staphylococcus a

Formula: C₃₆H₃₄N₂O₆

Purity: Min. 98.0 Area-%

Molecular weight: 590.67 g/mol

Ref: 3D-FLK-1750-PI