CAS 78111-17-8

1,7-Dioxaspiro[5.5]undec-10-ene-2-propanoic acid, α,5-dihydroxy-α,10-dimethyl-8-[(1R,2E)-1-methyl-3-[(2R,4'aR,5R,6'S,8'R,8'aS)-octahydro-8'-hydroxy-6'-[(1S,3S)-1-hydroxy-3-[(2S,3R,6S)-3-methyl-1,7-dioxaspiro[5.5]undec-2-yl]butyl]-7'-methylenespiro[furan-2(3H),2'(3'H)-pyrano[3,2-b]pyran]-5-yl]-2-propenyl]-, (αR,2S,5R,6R,8S)-

Description:

1,7-Dioxaspiro[5.5]undec-10-ene-2-propanoic acid, α,5-dihydroxy-α,10-dimethyl-8-[(1R,2E)-1-methyl-3-[(2R,4'aR,5R,6'S,8'R,8'aS)-octahydro-8'-hydroxy-6'-[(1S,3S)-1-hydroxy-3-[(2S,3R,6S)-3-methyl-1,7-dioxaspiro[5.5]undec-2-yl]butyl]-7'-methylenespiro[furan-2(3H),2'(3'H)-pyrano[3,2-b]pyran]-5-yl]-2-propenyl]-, (αR,2S,5R,6R,8S)- is a complex organic compound characterized by its intricate molecular structure, which includes multiple functional groups such as dioxaspiro, hydroxyl, and propanoic acid moieties. This compound exhibits chirality, indicated by its stereochemical descriptors, suggesting that it can exist in multiple enantiomeric forms. Its structural complexity may confer unique chemical properties, potentially influencing its reactivity and interactions with biological systems. The presence of multiple rings and stereocenters suggests that it may have applications in pharmaceuticals or as a synthetic intermediate in organic chemistry. Additionally, the compound's CAS number, 78111-17-8, allows for easy identification and reference in chemical databases. Overall, this substance represents a fascinating example of modern organic synthesis and structural diversity in chemical compounds.

Formula: C₄₄H₆₈O₁₃

InChI: InChI=1/C44H68O13/c1-25-21-34(55-44(23-25)35(46)12-11-31(54-44)24-41(6,50)40(48)49)26(2)9-10-30-14-18-43(53-30)19-15-33-39(57-43)36(47)29(5)38(52-33)32(45)22-28(4)37-27(3)13-17-42(56-37)16-7-8-20-51-42/h9-10,23,26-28,30-39,45-47,50H,5,7-8,11-22,24H2,1-4,6H3,(H,48,49)/b10-9+/t26-,27-,28+,30+,31+,32+,33-,34+,35-,36-,37?,38+,39?,41-,42+,43-,44-/m1/s1

InChI key: InChIKey=QNDVLZJODHBUFM-WFXQOWMNSA-N

SMILES: O[C@H]1[C@@]2(O[C@]([C@@H](/C=C/[C@@H]3O[C@]4(CC3)O[C@@]5([C@@](CC4)(O[C@]([C@H](C[C@H](C)[C@]6(O[C@]7(CC[C@H]6C)CCCCO7)[H])O)(C(=C)[C@H]5O)[H])[H])[H])C)(CC(C)=C2)[H])O[C@H](C[C@@](C(O)=O)(C)O)CC1

Synonyms:

• (αR,2S,5R,6R,8S)-α,5-Dihydroxy-α,10-dimethyl-8-[(1R,2E)-1-methyl-3-[(2R,4′aR,5R,6′S,8′R,8′aS)-octahydro-8′-hydroxy-6′-[(1S,3S)-1-hydroxy-3-[(2S,3R,6S)-3-methyl-1,7-dioxaspiro[5.5]undec-2-yl]butyl]-7′-methylenespiro[furan-2(3H),2′(3′H)-pyrano[3,2-b]pyran]-5-yl]-2-propen-1-yl]-1,7-dioxaspiro[5.5]undec-10-ene-2-propanoic acid
• 1,7-Dioxaspiro[5.5]undec-10-ene-2-propanoic acid, α,5-dihydroxy-α,10-dimethyl-8-[(1R,2E)-1-methyl-3-[(2R,4′aR,5R,6′S,8′R,8′aS)-octahydro-8′-hydroxy-6′-[(1S,3S)-1-hydroxy-3-[(2S,3R,6S)-3-methyl-1,7-dioxaspiro[5.5]undec-2-yl]butyl]-7′-methylenespiro[furan-2(3H),2′(3′H)-pyrano[3,2-b]pyran]-5-yl]-2-propen-1-yl]-, (αR,2S,5R,6R,8S)-
• 1,7-Dioxaspiro[5.5]undec-10-ene-2-propanoic acid, α,5-dihydroxy-α,10-dimethyl-8-[(1R,2E)-1-methyl-3-[(2R,4′aR,5R,6′S,8′R,8′aS)-octahydro-8′-hydroxy-6′-[(1S,3S)-1-hydroxy-3-[(2S,3R,6S)-3-methyl-1,7-dioxaspiro[5.5]undec-2-yl]butyl]-7′-methylenespiro[furan-2(3H),2′(3′H)-pyrano[3,2-b]pyran]-5-yl]-2-propenyl]-, (αR,2S,5R,6R,8S)-
• 1,7-Dioxaspiro[5.5]undec-10-ene-2-propanoic acid, α,5-dihydroxy-α,10-dimethyl-8-[1-methyl-3-[octahydro-8'-hydroxy-6'-[1-hydroxy-3-(3-methyl-1,7-dioxaspiro[5.5]undec-2-yl)butyl]-7'-methylenespiro[furan-2(3H),2'(3'H)-pyrano[3,2-b]pyran]-5-yl]-2-propenyl]-, [2'R-[2'α[R*[1R*[2S*(R*),5R*,6R*,8S*],2E]],4'aβ,6'β[1S*,3S*(2S*,3R*,6S*)],8'α,8'aα]]-
• 1,7-Dioxaspiro[5.5]undec-10-ene-2-propanoic acid, α,5-dihydroxy-α,10-dimethyl-8-[1-methyl-3-[octahydro-8′-hydroxy-6′-[1-hydroxy-3-(3-methyl-1,7-dioxaspiro[5.5]undec-2-yl)butyl]-7′-methylenespiro[furan-2(3H),2′(3′H)-pyrano[3,2-b]pyran]-5-yl]-2-propenyl]-, [2′R-[2′α[R*[1R*[2S*(R*),5R*,6R*,8S*],2E]],4′aβ,6′β[1S*,3S*(2S*,3R*,6S*)],8′α,8′aα]]-
• 1,7-Dioxaspiro[5.5]undecane, acanthifolicin deriv.
• 35-Demethyl-DTX 1
• 35-Demethyldinophysistoxin 1
• Acanthifolicin, 9,10-deepithio-9,10-didehydro-
• Nsc 677083
• Okadaic acid
• Spiro[furan-2(3H),2′(3′H)-pyrano[3,2-b]pyran], acanthifolicin deriv.
• (2R)-2-hydroxy-3-[(2S,5R,6R,8S)-5-hydroxy-8-{(2R,3E)-4-[(2R,4a'R,5R,6'S,8'R,8a'S)-8'-hydroxy-6'-{(1S,3S)-1-hydroxy-3-[(2S,3R,6S)-3-methyl-1,7-dioxaspiro[5.5]undec-2-yl]butyl}-7'-methylideneoctahydro-3H,3'H-spiro[furan-2,2'-pyrano[3,2-b]pyran]-5-yl]but-3-en-2-yl}-10-methyl-1,7-dioxaspiro[5.5]undec-10-en-2-yl]-2-methylpropanoic acid
• 78111-17-8
• 1,7-Dioxaspiro[5.5]undec-10-ene-2-propanoic acid, alpha,5-dihydroxy-alpha,10-dimethyl-8-[(1R,2E)-1-methyl-3-[(2R,4a'R,5R,6'S,8'R,8a'S)-octahydro-8'-hydroxy-6'-[(1S,3S)-1-hydroxy-3-[(2S,3R,6S)-3-methyl-1,7-dioxaspiro[5.5]undec-2-yl]butyl]-7'-methylenespiro[furan-2(3H),2'(3'H)-pyrano[3,2-b]pyran]-5-yl]-2-propen-1-yl]-, (alphaR,2S,5R,6R,8S)-
• OKADAIC ACID, 25 UG*
• 9,10-DEEPITHIO-9,10-DIDEHYDROACANTHIOFOLICIN
• Okadaic acid, free acid >98%
• Okadic acid
• OA
• OKADAIC ACID >95% PROTEIN PHOSPHATASE I
• 1,7-Dioxaspiro5.5undec-10-ene-2-propanoic acid, .alpha.,5-dihydroxy-.alpha.,10-dimethyl-8-(1R,2E)-1-methyl-3-(2R,4aR,5R,6S,8R,8aS)-octahydro-8-hydroxy-6-(1S,3S)-1-hydroxy-3-(2S,3R,6S)-3-methyl-1,7-dioxaspiro5.5undec-2-ylbutyl-7-methylenespirofuran-2(3H),2
• 9,10-DEEPITHIO-9,10-DIDEHYDROACANTHIFOLICIN
• OKADAIC ACID FREE ACID
• Okadaic acid,97%
• OKADAICACID,HIGHPURITY
• 9,10-deepithio-9,10-didehydro-acanthifolici
• OKADAIC ACID AMMONIUM SALT WATER-SOLUBLE ANALOG
• OKADAIC ACID, 98+%
• OKADAIC ACID, PROROCENTRUM CONCAVUM
• Ocadaic Acid
• HALOCHONDRINE A
• Okadaic acid from Prorocentrum concavum,OA
• Okadaic acid 35-Demethyl-DTX 1 NSC 677083 35-Demethyldinophysistoxin 1
• OKADAIC ACID SODIUM SALT 98+%
• Blue mussel, homogenized (Okadaic acid)
• 1,7-Dioxaspiro[5.5]undec-10-ene-2-propanoicacid, a,5-dihydroxy-a,10-dimethyl-8-[(1R,2E)-1-methyl-3-[(2R,4'aR,5R,6'S,8'R,8'aS)-octahydro-8'-hydroxy-6'-[(1S,3S)-1-hydroxy-3-[(2S,3R,6S)-3-methyl-1,7-dioxaspiro[5.5]undec-2-yl]butyl]-7'-methylenespiro[furan-2(
• OKADAIC ACID FROM PROROCENTRUM SP.
• 9,45-Seco-10-demercapto-9,10-didehydroacanthifolicin
• Okadaicacid,Prorocentrumconcavum,highpurity

Okadaic acid, 98%

CAS: 78111-17-8

Okadaic acid, is used as an activator of PKC and inhibitor of PP1 and PP2A phosphatases. The hydrophobic backbone of okadaic acid enables it to enter cells where it stimulates intracellular protein phosphorylation. It mimics the effects of insulin, enhances transmitter release at neuromuscular junct

Formula: C₄₄H₆₈O₁₃

Purity: 98%

Color and Shape: White, Solid

Molecular weight: 805.02

Ref: 02-J60155

Okadaic acid

CAS: 78111-17-8

Formula: C₄₄H₆₈O₁₃

Color and Shape: Solid

Molecular weight: 805.0029

Ref: IN-DA003AXF

Okadaic acid, Prorocentrum concavum, high purity

CAS: 78111-17-8

Formula: C₄₄H₆₈O₁₃

Purity: >98%

Molecular weight: 805.015

Ref: 10-M02211

Okadaic acid

CAS: 78111-17-8

Formula: C₄₄H₆₈O₁₃

Purity: ≥ 97.0%

Color and Shape: White crystalline powder or solid

Molecular weight: 805.02

Ref: 7W-GL7691

Okadaic acid, free acid

CAS: 78111-17-8

Okadaic acid, free acid

Formula: C₄₄H₆₈O₁₃

Purity: >98%

Color and Shape: white lyophilized solid

Molecular weight: 805.00g/mol

Ref: 54-BIM1576

Okadaic Acid

CAS: 78111-17-8

Applications Okadaic acid is a widely distributed marine toxin produced by several phytoplanktonic species and responsible for diarrheic shellfish poisoning in humans. At the molecular level, Okadaic acid is a potent and specific inhibitor of various types of serine/threonine protein phosphatases. Due to this enzymatic inhibition, Okadaic acid was reported to induce numerous alterations in relevant cellular physiological processes, including metabolic pathways such as glucose uptake, lipolysis and glycolysis, heme metabolism and glycogen and protein synthesis. OA. EU regulated marine toxin.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Valdiglesia, V., et al.: J. Toxicol. Enviro. Health., 75, 844 (2012); Kamat, P.K., et al.: Life. Sci., 90, 713 (2012); Valdiglesias, V., et al.: BMC. Genomics., 13, 46 (2012);

Formula: C₄₄H₆₈O₁₃

Color and Shape: Neat

Molecular weight: 805.00

Ref: TR-O515500

Okadaic acid

CAS: 78111-17-8

Inhibitor of PP1 and PP2A protein phosphatases

Formula: C₄₄H₆₈O₁₃

Purity: Min. 95%

Molecular weight: 805 g/mol

Ref: 3D-FO73140

Okadaic acid

CAS: 78111-17-8

Okadaic acid, a polyether marine toxin, is a highly potent and selective protein phosphatase (PP) inhibitor.

Formula: C₄₄H₆₈O₁₃

Purity: 98%

Color and Shape: White Crystals Or Powder

Molecular weight: 805

Ref: TM-T16381