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CAS 78114-46-2

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3-Chloro-2-oxopropyl triphenylphosphonium chloride

Description:
3-Chloro-2-oxopropyl triphenylphosphonium chloride is a quaternary ammonium compound characterized by its triphenylphosphonium cation and a chloro-substituted oxopropyl group. This compound typically appears as a white to off-white solid and is soluble in polar organic solvents. It is known for its utility in organic synthesis, particularly in the formation of phosphonium ylides, which are valuable intermediates in various reactions, including the Wittig reaction for alkene synthesis. The presence of the chlorine atom enhances its reactivity, making it a useful reagent in nucleophilic substitution reactions. Additionally, the triphenylphosphonium moiety contributes to its lipophilicity, allowing for potential applications in biological systems, such as targeting mitochondria. Safety data indicates that, like many phosphonium salts, it should be handled with care due to potential toxicity and irritant properties. Overall, 3-Chloro-2-oxopropyl triphenylphosphonium chloride is a versatile compound in synthetic organic chemistry with specific reactivity patterns and applications.
Formula:C21H19Cl2OP
InChI:InChI=1/C21H19ClOP.ClH/c22-16-18(23)17-24(19-10-4-1-5-11-19,20-12-6-2-7-13-20)21-14-8-3-9-15-21;/h1-15H,16-17H2;1H/q+1;/p-1
Synonyms:
  • (3-Chloro-2-Oxopropyl)(Triphenyl)Phosphonium Chloride
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