CAS 78148-37-5
:L-Tyrosine, 3-methoxy-, methyl ester
Description:
L-Tyrosine, 3-methoxy-, methyl ester, with the CAS number 78148-37-5, is a derivative of the amino acid L-tyrosine, which is an important building block for proteins and a precursor for neurotransmitters. This compound features a methoxy group at the 3-position of the aromatic ring and a methyl ester functional group, which can influence its solubility and reactivity. Typically, such esters are more lipophilic than their parent acids, potentially enhancing their bioavailability. L-Tyrosine itself is known for its role in the synthesis of catecholamines, including dopamine, norepinephrine, and epinephrine, and is involved in various metabolic pathways. The presence of the methoxy group may also impart unique properties, such as altered pharmacokinetics or biological activity. In terms of physical properties, it is likely to be a white to off-white solid, soluble in organic solvents, and may exhibit moderate stability under standard conditions. As with many chemical substances, safety data should be consulted for handling and usage guidelines.
Formula:C11H15NO4
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3-O-Methyl-L-DOPA Methyl Ester
CAS:Controlled ProductApplications Protected 3-O-Methyl-L-DOPA (M303815). 3-O-Methyl-L-DOPA is the major metabolite of L-DOPA via catechol O-methyltransferase (COMT). 3-Methoxy-L-tyrosine is neither a substrate for nor an inhibitor of L-amino acid decarboxylase activity. Inhibition of COMT enhances the anti-Parkinson activity of L-DOPA.
References Soares-da Silva, P., et al.: Brain Res., 863, 293 (2000), Deleu, D., et al.: Clin. Pharmacokinet., 41, 261 (2002),Formula:C11H15NO4Color and Shape:NeatMolecular weight:225.24
