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CAS 78164-00-8

:

vineomycin A1

Description:
Vineomycin A1 is a naturally occurring antibiotic compound that belongs to the class of glycopeptide antibiotics. It is produced by the fermentation of certain strains of the bacterium Streptomyces. This compound exhibits potent antibacterial activity, particularly against Gram-positive bacteria, and has been studied for its potential use in cancer therapy due to its cytotoxic properties. Vineomycin A1 is characterized by its complex structure, which includes a glycosylated moiety that contributes to its biological activity. The mechanism of action involves interference with bacterial cell wall synthesis, leading to cell lysis. Additionally, vineomycin A1 has shown some efficacy in inhibiting the growth of tumor cells, making it a subject of interest in oncological research. Its stability and solubility in various solvents are important for its application in both laboratory and clinical settings. However, like many antibiotics, the emergence of resistance and potential side effects necessitate careful consideration in its therapeutic use.
Formula:C49H58O18
InChI:InChI=1/C49H58O18/c1-22-30(50)9-13-37(60-22)64-33-11-15-39(62-24(33)3)66-46-26(5)59-35(19-32(46)52)27-7-8-28-41(43(27)54)44(55)29-17-18-48(57)21-47(6,20-36(53)49(48,58)42(29)45(28)56)67-40-16-12-34(25(4)63-40)65-38-14-10-31(51)23(2)61-38/h7-10,13-14,17-18,22-26,32-35,37-40,46,52,54,57-58H,11-12,15-16,19-21H2,1-6H3/t22-,23-,24-,25-,26+,32+,33-,34-,35+,37-,38-,39-,40-,46+,47-,48-,49-/m0/s1
Synonyms:
  • Antibiotic OS 4742 A(sub 1)
  • Brn 5724539
  • Os-4742 A1
  • P 1894B
  • Vineomycin A(sub 1)
  • Benz(a)anthracene-1,7,12(2H)-trione, 9-(2,6-dideoxy-4-O-((2S-(2-alpha,5-beta(2S*,6R*),6-beta))-5-((5,6-dihydro-6-methyl-5-oxo-2H-pyran-2-yl)oxy)tetrahydro-6-methyl-2H-pyran-2-yl)-beta-D-arabino-hexopyranosyl)-3-((5-((5,6-dihydro-6-methyl-5-oxo-2H-pyran-2-yl)oxy)tetrahydro-6-methyl-2H-pyran-2-yl)oxy)-3,4,4a,12b-tetrahydro-4a,8,12b-trihydroxy-3-methyl-, (3R-(3-alpha(2S*,5S*(2R*,6S*)6S*),4a-alpha,12a-alpha))-
  • (1R)-1,5-anhydro-2,6-dideoxy-4-O-[(2S,5S,6S)-6-methyl-5-{[(2R,6S)-6-methyl-5-oxo-5,6-dihydro-2H-pyran-2-yl]oxy}tetrahydro-2H-pyran-2-yl]-1-[(3R,4aR,12bS)-4a,8,12b-trihydroxy-3-methyl-3-{[(2S,5S,6S)-6-methyl-5-{[(2R,6S)-6-methyl-5-oxo-5,6-dihydro-2H-pyran-2-yl]oxy}tetrahydro-2H-pyran-2-yl]oxy}-1,7,12-trioxo-1,2,3,4,4a,7,12,12b-octahydrotetraphen-9-yl]-D-arabino-hexitol
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Found 4 products.
  • Vineomycin A1; OS-4742-A1; P-1894-B

    CAS:
    Formula:C49H58O18
    Purity:97.2%
    Color and Shape:Orange. Amorphous solid
    Molecular weight:935.0

    Ref: 8R-CL0037

    1mg
    To inquire
    5mg
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  • Vineomycin A1

    CAS:
    <p>Vineomycin A1 (OS-4742 A1) is an antibiotic effective against Gram-positive bacteria, identified in *Streptomyces matensis* subsp. vineus. It has also demonstrated antitumor activity in mice and holds potential for research in skin fibrosis.</p>
    Formula:C49H58O18
    Color and Shape:Solid
    Molecular weight:934.974
  • Vineomycin A1

    CAS:
    Vineomycin A1
    Formula:C49H58O18
    Purity:>80%
    Color and Shape: yellow solid
    Molecular weight:934.97g/mol

    Ref: 54-BIBR1111

    ne
    To inquire
  • Vineomycin A1

    CAS:
    <p>Vineomycin A1 is a cytotoxic antibiotic, which is isolated from the fermentation broth of certain Streptomyces species. This compound is a member of the anthracycline class of antibiotics, known for their potent antitumor activity. Vineomycin A1 exerts its effects by intercalating into DNA, disrupting the DNA replication process and ultimately inducing apoptosis in rapidly dividing cells. This mode of action makes it a valuable tool in studying cellular responses to DNA damage and has potential implications in cancer research. Leveraging its ability to target malignant cells, Vineomycin A1 is primarily examined for its therapeutic potential in oncology, particularly in treating certain types of cancers that are resistant to standard therapies. As a research chemical, it enables scientists to gain insights into the mechanisms of drug resistance and DNA repair pathways, contributing to the development of novel cancer treatment strategies.</p>
    Formula:C49H58O18
    Purity:Min. 95%
    Molecular weight:935.00 g/mol

    Ref: 3D-DDA16400

    5mg
    1,674.00€
    10mg
    2,609.00€
    25mg
    4,891.00€
    50mg
    7,825.00€