CAS 781661-94-7

Sepantronium bromide

Description:

Sepantronium bromide, with the CAS number 781661-94-7, is a chemical compound that belongs to the class of quaternary ammonium compounds. It is characterized by its cationic nature, which allows it to interact with negatively charged surfaces, making it useful in various applications, particularly in the fields of pharmaceuticals and biochemistry. This compound is often studied for its potential antimicrobial properties, as quaternary ammonium compounds are known for their ability to disrupt microbial cell membranes. Sepantronium bromide is typically presented as a white to off-white solid or powder and is soluble in water, which enhances its applicability in aqueous formulations. Its stability under normal conditions makes it suitable for use in various formulations, although care must be taken regarding its handling due to potential toxicity and irritant properties. As with many chemical substances, proper safety measures should be observed when working with Sepantronium bromide to mitigate any health risks associated with exposure.

Formula: C₂₀H₁₉N₄O₃·Br

InChI: InChI=1S/C20H19N4O3.BrH/c1-13-23(9-10-27-2)17-18(24(13)12-14-11-21-7-8-22-14)20(26)16-6-4-3-5-15(16)19(17)25;/h3-8,11H,9-10,12H2,1-2H3;1H/q+1;/p-1

InChI key: InChIKey=QBIYUDDJPRGKNJ-UHFFFAOYSA-M

SMILES: C([N+]=1C2=C(N(CCOC)C1C)C(=O)C=3C(C2=O)=CC=CC3)C=4C=NC=CN4.[Br-]

Synonyms:

• 1-(2-Methoxyethyl)-2-methyl-4,9-dioxo-3-(pyrazin-2-ylmethyl)-4,9-dihydro-1H-naphtho(2,3-d)imidazolium bromide
• 11-(2-Methoxyethyl)-2-methyl-4,9-dioxo-3-(pyrazin-2-ylmethyl)-4,9-dihydro-1H-naphtho(2,3-d)imidazolium bromide
• 1H-Naphth[2,3-d]imidazolium, 4,9-dihydro-1-(2-methoxyethyl)-2-methyl-4,9-dioxo-3-(2-pyrazinylmethyl)-, bromide (1:1)
• 1H-Naphth[2,3-d]imidazolium, 4,9-dihydro-1-(2-methoxyethyl)-2-methyl-4,9-dioxo-3-(pyrazinylmethyl)-, bromide
• Sepantronium bromide
• YM 155 monobromide
• Ym-155
• Ym155

3-(2-methoxyethyl)-2-methyl-4,9-dioxo-1-(pyrazin-2-ylmethyl)naphtho[2,3-d]imidazol-1-ium bromide

CAS: 781661-94-7

Formula: C₂₀H₁₉BrN₄O₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 443.2939

Ref: IN-DA0036ME

Sepantronium Bromide

CAS: 781661-94-7

Sepantronium Bromide

Purity: 98%

Color and Shape: Solid

Molecular weight: 443.29g/mol

Ref: 54-BIFK0009

Sepantronium bromide

CAS: 781661-94-7

Sepantronium bromide

Purity: ≥98%

Molecular weight: 443.26g/mol

Ref: 54-BUP09726

YM155 (Sepantronium Bromide)

CAS: 781661-94-7

Formula: C₂₀H₁₉BrN₄O₃

Molecular weight: 443.30

Ref: 4Z-Y-003001

Sepantronium bromide

CAS: 781661-94-7

Sepantronium bromide (YM155) is a small-molecule proapoptotic agent with potential antineoplastic activity.

Formula: C₂₀H₁₉BrN₄O₃

Purity: 99.68% - 99.85%

Color and Shape: Solid

Molecular weight: 443.26

Ref: TM-T2111

YM155

Controlled Product

CAS: 781661-94-7

Applications YM155 is a novel small-molecule survivin suppressant that suppressed expression of survivin and induced apoptosis in PC-3 and PPC-1 human HRPC. cell lines. Potent Survivin Inhibitor.
References Takhito, N., et al.: Cancer. Res., 67, 8014 (2007); Kita, A., et al.: J. Pharmacol. Exper. Therap., 343, 178 (2012); Kumar, B., et al.: Molec. Cancer. Therap., 11, 1988 (2012);

Formula: C₂₀H₁₉BrN₄O₃

Color and Shape: Neat

Molecular weight: 443.29

Ref: TR-Y100300

YM155

CAS: 781661-94-7

A novel survivin suppressant with an IC50 of 0.54 nM for the negative regulation of the survivin promoter.

Formula: C₂₀H₁₉BrN₄O₃

Purity: Min. 95%

Color and Shape: Off-White Powder

Molecular weight: 443.29 g/mol

Ref: 3D-FS145344

YM155-d3

Controlled Product

CAS: 781661-94-7

Formula: C₂₀D₃H₁₅N₄O₃·Br

Color and Shape: Neat

Molecular weight: 445.304

Ref: TR-Y100302