CAS 78214-33-2

Ginsenoside Rh2

Description:

Ginsenoside Rh2 is a natural compound classified as a triterpenoid saponin, primarily derived from the roots of Panax ginseng, a plant known for its medicinal properties. It is characterized by its complex molecular structure, which includes a steroid-like backbone with sugar moieties attached, contributing to its biological activity. Ginsenoside Rh2 is recognized for its potential pharmacological effects, including anti-cancer, anti-inflammatory, and neuroprotective properties. It has been studied for its ability to modulate various signaling pathways, influencing cell proliferation and apoptosis in cancer cells. Additionally, Ginsenoside Rh2 exhibits antioxidant activity, which may help in reducing oxidative stress. The compound is typically found in low concentrations in ginseng extracts, necessitating advanced extraction and purification techniques for research and therapeutic applications. Its safety profile and efficacy are subjects of ongoing research, highlighting the need for further studies to fully understand its mechanisms and potential health benefits.

Formula: C₃₆H₆₂O₈

InChI: InChI=1S/C36H62O8/c1-20(2)10-9-14-36(8,42)21-11-16-35(7)27(21)22(38)18-25-33(5)15-13-26(32(3,4)24(33)12-17-34(25,35)6)44-31-30(41)29(40)28(39)23(19-37)43-31/h10,21-31,37-42H,9,11-19H2,1-8H3/t21-,22+,23+,24-,25+,26-,27-,28+,29-,30+,31-,33-,34+,35+,36-/m0/s1

InChI key: InChIKey=CKUVNOCSBYYHIS-IRFFNABBSA-N

SMILES: C[C@]12[C@@]3(C)[C@@]([C@@]([C@@](CCC=C(C)C)(C)O)(CC3)[H])([C@H](O)C[C@@]1([C@]4(C)[C@@](CC2)(C(C)(C)[C@@H](O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)CC4)[H])[H])[H]

Synonyms:

• (3beta,12beta)-12,20-Dihydroxydammar-24-en-3-yl beta-D-glucopyranoside
• (3β,12β)-12,20-Dihydroxydammar-24-en-3-yl β-<span class="text-smallcaps">D</span>-glucopyranoside
• 20(S)-Ginsenoside Rh₂
• 20(S)-Rh2
• 3-O-β-<span class="text-smallcaps">D</span>-Glucopyranosyl-20(S)-protopanaxadiol
• Dammarane, β-<span class="text-smallcaps">D</span>-glucopyranoside deriv.
• Ginsenoside 20-Rh2
• Ginsenoside Rh₂
• Ginsenoside rh2(S)
• β-<span class="text-smallcaps">D</span>-Glucopyranoside, (3β,12β)-12,20-dihydroxydammar-24-en-3-yl
• Dammarane, β-D-glucopyranoside deriv.
• Ginsenoside Rh2
• β-D-Glucopyranoside, (3β,12β)-12,20-dihydroxydammar-24-en-3-yl
• 3-O-β-D-Glucopyranosyl-20(S)-protopanaxadiol
• (3β,12β)-12,20-Dihydroxydammar-24-en-3-yl β-D-glucopyranoside
• β-D-Glucopyranoside, (3β,12β)-12,20-
• 12β,20-Dihydroxy-5α-dammar-24-en-3β-yl β-D-glucopyranoside
• R-form-Ginsenoside Rh2
• dihydroxydammar-24-en-3-yl

Ginsenoside Rh2

CAS: 78214-33-2

Ginsenoside Rh2 analytical standard provided with w/w absolute assay, to be used for quantitative titration.

Formula: C₃₆H₆₂O₈

Purity: (HPLC) ≥98%

Color and Shape: Powder

Molecular weight: 622.89

Ref: 11-0154S

Ginsenoside Rh2

CAS: 78214-33-2

Ginsenoside Rh2

Purity: ≥98%

Molecular weight: 622.87g/mol

Ref: 54-BUP06318

Ginsenoside Rh2

CAS: 78214-33-2

Ginsenoside Rh2 is one of the most active components of red ginseng, controlling cancer and other metabolic diseases including osteoclast differentiation; ginsenoside Rh2 can suppress RANKL-induced osteoclast differentiation in vitro and in vivo through the regulation of c-Fos and NFATc1 expressions, not excluding the involvement of NF-κB and ERK, it is also suggested to be developed as a therapeutic drug for prevention and treatment of osteoporosis.

Formula: C₃₆H₆₂O₈

Purity: 95%~99%

Color and Shape: White powder

Molecular weight: 622.884

Ref: BP-BP0668

20(s)-Ginsenoside Rh2

CAS: 78214-33-2

Formula: C₃₆H₆₂O₈

Purity: ≥ 98.0%

Color and Shape: White to off-white powder

Molecular weight: 622.87

Ref: 7W-GC1836

Ginsenoside Rh2

CAS: 78214-33-2

Formula: C₃₆H₆₂O₈

Molecular weight: 622.88

Ref: 4Z-G-157005

Ginsenoside Rh2-d6

CAS: 78214-33-2

Formula: C₃₆H₅₆D₆O₈

Molecular weight: 628.92

Ref: 4Z-G-157007

Ginsenoside Rh2

CAS: 78214-33-2

Ginsenoside Rh2 (20(S)-Ginsenoside Rh2), an extract of red Panax ginseng, is a potent anti-inflammatory and anticancer drug.

Formula: C₃₆H₆₂O₈

Purity: 99.20% - 99.76%

Color and Shape: White Powder

Molecular weight: 622.87

Ref: TM-T2959

Ginsenoside rh2

CAS: 78214-33-2

Natural glycoside

Formula: C₃₆H₆₂O₈

Purity: ≥ 90.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 622.89

Ref: 5G-89683

20(S)-Ginsenoside Rh2

Controlled Product

CAS: 78214-33-2

Applications 20(S)-Ginsenoside Rh2 is a bioactive metabolite of the ginsenoside component of Panax ginseng that has been shown to exhibit antibacterial effects in vitro.
References Zhang, J. et al.: Eur. J. Pharm., 740, 277 (2014);

Formula: C₃₆H₆₂O₈

Color and Shape: Neat

Molecular weight: 622.87

Ref: TR-G387585

20(s)-Ginsenoside Rh2

CAS: 78214-33-2

20(s)-Ginsenoside Rh2 is a bioactive compound classified as a saponin, which is derived from the root of the Panax ginseng plant. This compound exhibits a wide range of pharmacological activities attributed to its ability to modulate cellular pathways. It exerts its mode of action primarily through the regulation of apoptosis, modulation of immune responses, and inhibition of tumor growth. Mechanistically, it interacts with cellular receptors and signaling molecules, influencing pathways such as NF-κB and MAPK, which are crucial in cell proliferation and apoptosis.

Formula: C₃₆H₆₂O₈

Purity: Min. 98 Area-%

Color and Shape: Powder

Molecular weight: 622.89 g/mol

Ref: 3D-OG09293

20(S)-Ginsenoside Rh2-d6

Controlled Product

CAS: 78214-33-2

Formula: C₃₆D₆H₅₆O₈

Color and Shape: Neat

Molecular weight: 628.91

Ref: TR-G410290

Ginsenoside Rh2

CAS: 78214-33-2

Ginsenoside Rh2 is a bioactive compound, which is a triterpenoid saponin derived from the root of the Panax ginseng plant. It operates through multiple biochemical pathways, including the modulation of cell signaling cascades such as the inhibition of cell proliferation and the induction of apoptosis in cancer cells. These actions are primarily mediated through mitochondrial pathways and involve the regulation of pro-apoptotic and anti-apoptotic proteins.

Formula: C₃₆H₆₂O₈

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 622.87 g/mol

Ref: 3D-FG65764

(3β,12β)-12,20-Dihydroxydammar-24-en-3-yl β-D-glucopyranoside

CAS: 78214-33-2

Formula: C₃₆H₆₂O₈

Purity: 98%

Color and Shape: Solid

Molecular weight: 622.8727

Ref: IN-DA00393A