CAS 78246-49-8

Paroxetine hydrochloride

Description:

Paroxetine hydrochloride is a selective serotonin reuptake inhibitor (SSRI) primarily used in the treatment of major depressive disorder, anxiety disorders, and other mood-related conditions. It is characterized by its chemical formula, which includes a piperidine ring and a phenyl group, contributing to its pharmacological activity. The substance appears as a white to off-white crystalline powder and is soluble in water, making it suitable for various pharmaceutical formulations. Paroxetine hydrochloride works by inhibiting the reuptake of serotonin in the brain, thereby increasing serotonin levels and improving mood. It is typically administered in oral form, with dosage adjusted based on the specific condition being treated. Common side effects may include nausea, dizziness, and sexual dysfunction, among others. Due to its effects on serotonin levels, caution is advised when prescribing it alongside other medications that influence serotonin, to avoid potential interactions such as serotonin syndrome. Overall, paroxetine hydrochloride is a widely used antidepressant with a well-established efficacy profile.

Formula: C₁₉H₂₀FNO₃·ClH

InChI: InChI=1S/C19H20FNO3.ClH/c20-15-3-1-13(2-4-15)17-7-8-21-10-14(17)11-22-16-5-6-18-19(9-16)24-12-23-18;/h1-6,9,14,17,21H,7-8,10-12H2;1H/t14-,17-;/m0./s1

InChI key: InChIKey=GELRVIPPMNMYGS-RVXRQPKJSA-N

SMILES: C(OC=1C=C2C(=CC1)OCO2)[C@H]3[C@@H](CCNC3)C4=CC=C(F)C=C4.Cl

Synonyms:

• (-)-trans-4-(4-Fluorophenyl)-3-(3,4-methylenedioxyphenoxymethyl)piperidine hydrochloride
• (3S,4R)-3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)piperidine
• (3S-trans)-3-[(1,3-Benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)piperidine hydrochloride
• 3-[(1,3-Benzodioxol-5-Yloxy)Methyl]-4-(4-Fluorophenyl)Piperidine Hydrochloride
• Aropax 20
• BRL 29060 hydrochloride
• Brl 29060A
• Deroxat
• Paroxet
• Paroxetine HCl,Anhydrous
• Paroxetine Hydrochloride
• Paroxetine Hydrochloride Anhydrous
• Paxil
• Piperidine, 3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)-, hydrochloride (1:1), (3S,4R)-
• Piperidine, 3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)-, hydrochloride, (3S,4R)-
• Piperidine, 3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)-, hydrochloride, (3S-trans)-
• Seroxat
• Tagonis

Paroxetine Hydrochloride Hemihydrate

CAS: 110429-35-1, 61869-08-7, 78246-49-8

Formula: C₁₉H₂₀FNO₃·HClH₂O

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 374.84

Ref: 3B-P1977

PAROXETINE HYDROCHLORIDE (ANHYDROUS) CRS

CAS: 78246-49-8

PAROXETINE HYDROCHLORIDE (ANHYDROUS) CRS

Ref: 41-Y0000578

Paroxetine hydrochloride

CAS: 78246-49-8

Paroxetine hydrochloride (Paroxetine HCl) is a serotonin uptake inhibitor that is effective in the treatment of depression.

Formula: C₁₉H₂₁ClFNO₃

Purity: 98% - 99.99%

Color and Shape: White Crystalline Powder

Molecular weight: 365.826

Ref: TM-T1636

Paroxetine hydrochloride

CAS: 78246-49-8

Paroxetine hydrochloride

Purity: ≥98%

Molecular weight: 365.826g/mol

Ref: 54-BUP13970

(3S,4R)-3-((Benzo[D][1,3]Dioxol-5-Yloxy)Methyl)-4-(4-Fluorophenyl)Piperidine Hydrochloride

CAS: 78246-49-8

(3S,4R)-3-((Benzo[D][1,3]Dioxol-5-Yloxy)Methyl)-4-(4-Fluorophenyl)Piperidine Hydrochloride

Purity: 99%

Molecular weight: 365.83g/mol

Ref: 54-PC109212

Paroxetine hydrochloride

CAS: 78246-49-8

Formula: C₁₉H₂₀FNO₃·ClH

Color and Shape: Neat

Molecular weight: 365.83

Ref: 04-C15893720

Paroxetine Impurity 35

CAS: 78246-49-8

Formula: C₂₁H₂₄FNO₃

Color and Shape: White To Off-White Solid

Molecular weight: 357.43

Ref: 4Z-P-0228

Paroxetine Hydrochloride

Controlled Product

CAS: 78246-49-8

Applications A selective serotonin reuptake inhibitor. Used as an antidepressant.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Lassen, J.B.: Eur. J. Pharmacol., 47, 351 (1978), Lund, J., et al.: Acta Pharmacol. Toxicol., 51, 351, (1982),

Formula: C₁₉H₂₀FNO₃·ClH

Color and Shape: White To Off-White

Molecular weight: 365.83

Ref: TR-P205750

Paroxetine hydrochloride

Controlled Product

CAS: 78246-49-8

A serotonin reuptake inhibitor with anticholinergic activity and mild inhibitory activity on noradrenaline reuptake. Paroxetine has been used for the treatment of depression, anxiety disorders, post-traumatic stress disorder, premenstrual dysphoric disorder and obsessive-compulsive disorder.  Also inhibits nitric oxide synthase and cytochrome isoenzyme P450 2D6.

Formula: C₁₉H₂₀FNO₃·HCl

Purity: Min. 97%

Color and Shape: White Powder

Molecular weight: 365.83 g/mol

Ref: 3D-FP38223

Paroxetine Hydrochloride

CAS: 78246-49-8

Formula: C₁₉H₂₀FNO₃HCl

Molecular weight: 329.37 : 36.46

Ref: ST-EA-CP-P3019

USP Paroxetine System Suitability Mixture A

Controlled Product

CAS: 1322626-23-2, 78246-49-8

Formula: C₁₉H₁₉ClFNO₃C₂₀H₂₂ClNO₄C₁₉H₂₂ClNO₃

Color and Shape: Mixture

Ref: TR-P205785