CAS 78371-66-1
:Bucromarone
Description:
Bucromarone, with the CAS number 78371-66-1, is a chemical compound that belongs to the class of anticoagulants, specifically acting as a vitamin K antagonist. It is primarily used in the medical field for its ability to inhibit blood clot formation, making it useful in the prevention and treatment of thromboembolic disorders. The compound exhibits a relatively low solubility in water, which can influence its bioavailability and pharmacokinetics. Bucromarone's mechanism of action involves the inhibition of vitamin K epoxide reductase, leading to a decrease in the synthesis of vitamin K-dependent clotting factors. This results in an anticoagulant effect, which is critical in managing conditions such as deep vein thrombosis and pulmonary embolism. As with many anticoagulants, careful monitoring of dosage and potential interactions with other medications is essential to minimize the risk of bleeding complications. Overall, Bucromarone represents an important therapeutic agent in the management of coagulation disorders.
Formula:C29H37NO4
InChI:InChI=1/C29H37NO4/c1-5-7-14-30(15-8-6-2)16-11-17-33-29-21(3)18-23(19-22(29)4)28(32)27-20-25(31)24-12-9-10-13-26(24)34-27/h9-10,12-13,18-20H,5-8,11,14-17H2,1-4H3
SMILES:CCCCN(CCCC)CCCOc1c(C)cc(cc1C)C(=O)c1cc(=O)c2ccccc2o1
Synonyms:- Bucromarone [USAN:INN]
- 2-(4-(3-(Dibutylamino)propoxyl)-3,5-dimethylbenzoyl)chromone
- 2-(4-(3-Dibutylamino)propoxy)-3,5-dimethyl)benzoyl)-4H-chromen-4-on
- 4H-1-Benzopyran-4-one, 2-(4-(3-(dibutylamino)propoxy)-3,5-dimethylbenzoyl)-
- Bucromarona
- Bucromarona [Spanish]
- Bucromaronum
- Bucromaronum [Latin]
- Unii-Ji688O846T
- 2-{4-[3-(dibutylamino)propoxy]-3,5-dimethylbenzoyl}-4H-chromen-4-one
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Found 2 products.
Bucromarone
CAS:<p>Bucromarone is an anticancer drug that has been shown to inhibit the growth of cancer cells by targeting specific proteins and enzymes involved in tumor formation. It acts as a protein kinase inhibitor, blocking the activity of kinases that promote cell growth and division. Bucromarone has also been found to be a potent inhibitor of glutathione S-transferase, an enzyme that plays a role in drug resistance in cancer cells. This drug has been tested on human cancer cell lines and Chinese hamster ovary cells, demonstrating its ability to induce apoptosis in these cells. Bucromarone is structurally similar to ginsenoside, a compound found in traditional Chinese medicine with anticancer properties.</p>Formula:C29H37NO4Purity:Min. 95%Molecular weight:463.6 g/mol
