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CAS 784-57-6

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N-[2-Amino-4-(trifluoromethyl)-phenyl]-morpholine

Description:
N-[2-Amino-4-(trifluoromethyl)-phenyl]-morpholine, with the CAS number 784-57-6, is an organic compound characterized by its unique molecular structure that includes a morpholine ring and a trifluoromethyl-substituted phenyl group. This compound typically exhibits properties such as moderate solubility in polar organic solvents and may have limited solubility in water due to the presence of the hydrophobic trifluoromethyl group. It is often utilized in pharmaceutical research and development, particularly in the synthesis of biologically active molecules. The amino group in its structure can participate in hydrogen bonding, influencing its reactivity and interaction with biological targets. Additionally, the trifluoromethyl group can enhance lipophilicity and metabolic stability, making it a valuable moiety in drug design. Safety data sheets should be consulted for handling and storage guidelines, as compounds with trifluoromethyl groups can exhibit unique toxicological profiles. Overall, this compound's characteristics make it a subject of interest in medicinal chemistry and related fields.
Formula:C11H13F3N2O
InChI:InChI=1/C11H13F3N2O/c12-11(13,14)8-1-2-10(9(15)7-8)16-3-5-17-6-4-16/h1-2,7H,3-6,15H2
SMILES:c1cc(c(cc1C(F)(F)F)N)N1CCOCC1
Synonyms:
  • 4-[2-Amino-4-(trifluoromethyl)phenyl]morpholine~2-(4-Morpholino)-5-trifluoromethylaniline
  • 2-Morpholino-5-(trifluoromethyl)aniline
  • 3-Amino-4-(4-morpholino)benzotrifluoride
  • 2-(Morpholin-4-Yl)-5-(Trifluoromethyl)Aniline
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