CAS 784-71-4

2'-Fluoro-2'-deoxyuridine

Description:

2'-Fluoro-2'-deoxyuridine (FdU) is a nucleoside analog of thymidine, characterized by the presence of a fluorine atom at the 2' position of the deoxyribose sugar. This modification imparts unique properties to the molecule, making it a valuable compound in medicinal chemistry, particularly in antiviral and anticancer therapies. FdU is known to inhibit DNA synthesis by interfering with the action of thymidine kinases, which are crucial for the phosphorylation of nucleosides. As a result, it can disrupt the replication of viral DNA and the proliferation of cancer cells. The compound is typically administered in its phosphate form to enhance its bioavailability and efficacy. In terms of solubility, FdU is generally soluble in water and organic solvents, which facilitates its formulation for therapeutic use. Its mechanism of action and structural similarities to natural nucleosides allow it to be incorporated into DNA, leading to cytotoxic effects in rapidly dividing cells. Overall, 2'-Fluoro-2'-deoxyuridine serves as an important tool in both research and clinical settings for targeting specific cellular processes.

Formula: C₉H₁₁FN₂O₅

InChI: InChI=1/C9H11FN2O5/c10-6-7(15)4(3-13)17-8(6)12-2-1-5(14)11-9(12)16/h1-2,4,6-8,13,15H,3H2,(H,11,14,16)

SMILES: c1cn(C2C(C(C(CO)O2)O)F)c(=O)nc1O

Synonyms:

• 2'-Deoxy-2'-fluorouridine
• 2-FdU
• 1-(2-deoxy-2-fluoropentofuranosyl)pyrimidine-2,4(1H,3H)-dione
• 2'-Fluoro-5'-O-DMT-2'-deoxyuridine
• DMT-2'-F-dU
• 2-Fluoro-2-Deoxyuridine
• 2'-FLUORO-D-URIDINE
• 2''-DEOXY-2''-FLUOROURIDINE (2''-FLUORO-2''-DEOXYURIDINE)
• 2'-FUDR
• 1-(2'-FLUORO-2'-DESOXY-BETA-D-RIBOFURANOSYL)URACIL
• 2'-DEOXY-2'-FLUOROURIDINE (2'-FLUORO-2'-DEOXYURIDINE, 2'-FU)
• 2,4(1H,3H)-PYRIMIDINEDIONE, 1-(2-DEOXY-2-FLUORO-BETA-D-RIBOFURANOSYL)
• 2'-Deoxy-2'-fluoro-D-uridine
• URIDINE,2''-DEOXY-2''-FLUORO
• 2'-FLUORO-2'-DESOXY-URIDINE

2'-Deoxy-2'-fluorouridine

CAS: 784-71-4

Formula: C₉H₁₁FN₂O₅

Purity: >97.0%(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 246.19

Ref: 3B-D3615

2'-Fluoro-2'-deoxyuridine, 97%

CAS: 784-71-4

2'-Fluoro-2'-deoxyuridine is used as a component incorporated into therapeutic oligonucleotides to combat prostate and breast cancer. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the lega

Formula: C₉H₁₁FN₂O₅

Purity: 97%

Color and Shape: Powder or crystals or crystalline powder, White to off-white

Molecular weight: 246.19

Ref: 02-J65948

2'-Fluoro-2'-deoxyuridine

CAS: 784-71-4

Formula: C₉H₁₁FN₂O₅

Purity: 95%

Color and Shape: Solid

Molecular weight: 246.1924

Ref: IN-DA0035VT

2'-Deoxy-2'-fluorouridine

CAS: 784-71-4

2'-Deoxy-2'-fluorouridine

Purity: ≥98%

Molecular weight: 246.19g/mol

Ref: 54-BUP19100

2''-Fluoro-2''-deoxyuridine

CAS: 784-71-4

Formula: C₉H₁₁FN₂O₅

Purity: ≥ 99.0%

Color and Shape: White crystalline powder

Molecular weight: 246.19

Ref: 7W-GE3995

2'-Fluoro-2'-deoxyuridine

CAS: 784-71-4

2'-Fluoro-2'-deoxyuridine

Purity: 98%

Molecular weight: 246.19g/mol

Ref: 54-PC48732

Azvudine Impurity 1

CAS: 784-71-4

Formula: C₉H₁₁FN₂O₅

Molecular weight: 246.19

Ref: 4Z-A-360001

2'-Deoxy-2'-fluorouridine

CAS: 784-71-4

2'-Deoxy-2'-fluorouridine serves as an intermediate in the synthesis of antiviral agents targeting influenza viruses[1].

Formula: C₉H₁₁FN₂O₅

Purity: 99.93%

Color and Shape: Solid

Molecular weight: 246.19

Ref: TM-T38239

2'-Deoxy-2'-fluorouridine

CAS: 784-71-4

2'-Deoxy-2'-fluorouridine is a nucleoside analog that inhibits the replication of wild-type viruses by binding to the viral RNA.

Formula: C₉H₁₁FN₂O₅

Purity: Min. 95%

Color and Shape: White Off-White Powder

Molecular weight: 246.2 g/mol

Ref: 3D-ND06544

2′-Deoxy-2′-fluorouridine

CAS: 784-71-4

Formula: C₉H₁₁FN₂O₅

Purity: 95%

Color and Shape: Solid

Molecular weight: 246.194

Ref: 10-F211913

2'-Fluoro-2'-deoxyuridine-2-13C, 1,3-15N2

Controlled Product

CAS: 784-71-4

Formula: CC₈H₁₁F₁₅N₂O₅

Color and Shape: Neat

Molecular weight: 249.172

Ref: TR-F590277

Azvudine Impurity 1

CAS: 784-71-4

Formula: C₉H₁₁FN₂O₅

Molecular weight: 246.19

Ref: ST-EA-CP-A345005