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CAS 78415-72-2

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Milrinone

Description:
Milrinone is a phosphodiesterase inhibitor primarily used in the treatment of heart failure. It functions by increasing intracellular levels of cyclic adenosine monophosphate (cAMP), leading to enhanced cardiac contractility and vasodilation. This mechanism helps improve cardiac output and reduce the workload on the heart. Milrinone is typically administered intravenously and is often used in acute settings, such as during severe heart failure exacerbations or after cardiac surgery. The substance is characterized by its relatively short half-life, necessitating continuous infusion for sustained therapeutic effects. Milrinone is also known for its potential side effects, which may include arrhythmias, hypotension, and headache. Its pharmacokinetics involve rapid distribution and metabolism, primarily in the liver, with renal excretion of its metabolites. As a therapeutic agent, milrinone is valuable in managing patients with decompensated heart failure, particularly when other treatments are ineffective. However, careful monitoring is essential due to its potent effects on cardiovascular dynamics.
Formula:C12H9N3O
InChI:InChI=1/C12H9N3O/c1-8-11(9-2-4-14-5-3-9)6-10(7-13)12(16)15-8/h2-6H,1H3,(H,15,16)
InChI key:InChIKey=PZRHRDRVRGEVNW-UHFFFAOYSA-N
SMILES:CC1=C(C=C(C#N)C(=O)N1)C=2C=CN=CC2
Synonyms:
  • 1,6-Dihydro-2-methyl-6-oxo-(3,4'-bipyridine)-5-carbonitrile
  • 2-Hydroxy-6-methyl-5-(pyridin-4-yl)pyridine-3-carbonitrile
  • Corotrop
  • Corotrope
  • Milrila
  • Milrinon
  • Milrinona
  • Milrinone
  • Primacor
  • Primacor IV
  • See more synonyms
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Found 15 products.
  • Milrinone

    CAS:
    Formula:C12H9N3O
    Purity:>98.0%(HPLC)(N)
    Color and Shape:White to Light yellow powder to crystal
    Molecular weight:211.22

    Ref: 3B-M1663

    1g
    213.00€
    100mg
    43.00€
  • Milrinone, 98+%

    CAS:
    <p>Potent cAMP-specific phosphodiesterase inhibitor</p>
    Formula:C12H9N3O
    Purity:98+%
    Color and Shape:Pale cream to cream, Powder or crystals or crystalline powder
    Molecular weight:211.22

    Ref: 02-J62659

    10mg
    153.00€
    50mg
    To inquire
  • Milrinone

    CAS:
    <p>Lactams not elsewhere specified or included</p>
    Formula:C12H9N3O
    Color and Shape:Powder
    Molecular weight:211.07456
  • Milrinone

    CAS:
    <p>Milrinone (Win 47203) is a Phosphodiesterase 3 Inhibitor. The mechanism of action of milrinone is as a Phosphodiesterase 3 Inhibitor.</p>
    Formula:C12H9N3O
    Purity:99.22% - 99.92%
    Color and Shape:Solid
    Molecular weight:211.22
  • Milrinone

    CAS:
    Formula:C12H9N3O
    Purity:99%
    Color and Shape:Solid
    Molecular weight:211.2194

    Ref: IN-DA003S4R

    1g
    49.00€
    5g
    107.00€
    10g
    160.00€
    25g
    208.00€
    50g
    331.00€
    100g
    506.00€
    100mg
    25.00€
    250mg
    34.00€
  • Milrinone

    CAS:
    Formula:C12H9N3O
    Color and Shape:Pale Yellow Solid
    Molecular weight:211.23

    Ref: 4Z-M-811

    5mg
    To inquire
    10mg
    To inquire
    25mg
    To inquire
    50mg
    To inquire
    100mg
    To inquire
  • Milrinone

    CAS:
    Formula:C12H9N3O
    Molecular weight:211.22

    Ref: 7W-GP3826

    ne
    To inquire
  • Milrinone

    CAS:
    <p>Milrinone</p>
    Purity:≥98%
    Molecular weight:211.22g/mol

    Ref: 54-BUP15786

    1g
    296.00€
    25mg
    57.00€
    50mg
    83.00€
    100mg
    124.00€
    200mg
    163.00€
    500mg
    254.00€
  • Milrinone

    CAS:
    <p>Milrinone</p>
    Purity:98%
    Color and Shape:White Solid
    Molecular weight:211.22g/mol

    Ref: 54-BIM0128

    1g
    85.00€
    5g
    120.00€
    25g
    295.00€
    100g
    984.00€
    250mg
    37.00€
  • Milrinone

    Controlled Product
    CAS:
    Formula:C12H9N3O
    Color and Shape:Neat
    Molecular weight:211.22

    Ref: 86-MM1539.00

    250mg
    To inquire
  • Milrinone

    Controlled Product
    CAS:
    <p>Applications Selective phosphodiesterase inhibitor with vasodilating and positive inotropic activity; cardiotonic. Potent PDE3 inhibitor.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Alousi, A.A., et al.: J. Cardiovasc Pharmacol., 5, 792 (1983), Maskin, C.S., et al.: Circulation, 67, 1065 (1983), Sinoway, L.S., et al.: J. Am. Coll. Cardiol., 2, 327 (1983), Baim, D.S., et al.: N. Engl. J. Med., 309, 748 (1983),<br></p>
    Formula:C12H9N3O
    Color and Shape:White
    Molecular weight:211.22

    Ref: TR-M344680

    5mg
    98.00€
    100mg
    191.00€
    250mg
    231.00€
  • Milrinone

    CAS:
    <p>Phosphodiesterase PDE3 inhibitor; inodilator</p>
    Formula:C12H9N3O
    Purity:Min. 95%
    Color and Shape:Off-White Powder
    Molecular weight:211.22 g/mol

    Ref: 3D-FM26007

    2g
    192.00€
    5g
    320.00€
    10g
    501.00€
    25g
    929.00€
    50g
    1,364.00€
  • Milrinone - Bio-X ™

    CAS:
    <p>Milrinone has an application for use in the treatment of heart failure. It has been shown to increase cardiac output and decrease left ventricular end diastolic pressure (LVEDP). Milrinone also increases the amount of oxygen delivered to the tissues by increasing cardiac contractility. <br>Milrinone is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready to use products for assay development, screening or other R&amp;D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.</p>
    Formula:C12H9N3O
    Purity:(%) Min. 95%
    Color and Shape:Powder
    Molecular weight:211.22 g/mol

    Ref: 3D-BM164671

    10mg
    135.00€
  • 3-Cyano-6-methyl-5-(4-pyridyl)-2-pyridone

    CAS:
    Formula:C12H9N3O
    Purity:97.0%
    Color and Shape:Crystalline
    Molecular weight:211.224

    Ref: 10-F036508

    1g
    43.00€
    5g
    110.00€
    25g
    267.00€
    100mg
    21.00€
    250mg
    28.00€
  • Milrinone-d4

    Controlled Product
    CAS:
    Formula:C12H5D4N3O
    Color and Shape:Neat
    Molecular weight:309.278

    Ref: TR-M344682

    100mg
    8,684.00€