CAS 784210-88-4

N-[1,4-Dihydro-3-[4-[[4-(2-methoxyethyl)-1-piperazinyl]methyl]phenyl]-4-oxoindeno[1,2-c]pyrazol-5-yl]-N′-4-morpholinylurea

Description:

N-[1,4-Dihydro-3-[4-[[4-(2-methoxyethyl)-1-piperazinyl]methyl]phenyl]-4-oxoindeno[1,2-c]pyrazol-5-yl]-N′-4-morpholinylurea, with CAS number 784210-88-4, is a synthetic organic compound characterized by its complex molecular structure, which includes multiple functional groups such as urea, morpholine, and piperazine. This compound exhibits properties typical of small-molecule pharmaceuticals, potentially including high solubility in organic solvents and moderate stability under standard laboratory conditions. Its structure suggests potential biological activity, possibly as an inhibitor or modulator in various biochemical pathways, making it of interest in medicinal chemistry. The presence of the indeno-pyrazole moiety may contribute to its pharmacological properties, while the morpholine and piperazine rings could enhance its interaction with biological targets. As with many synthetic compounds, its safety profile, including toxicity and environmental impact, would need to be assessed through rigorous testing. Overall, this compound represents a class of molecules that may have therapeutic applications, pending further research and development.

Formula: C₂₉H₃₅N₇O₄

InChI: InChI=1S/C29H35N7O4/c1-39-16-13-34-9-11-35(12-10-34)19-20-5-7-21(8-6-20)26-25-27(32-31-26)22-3-2-4-23(24(22)28(25)37)30-29(38)33-36-14-17-40-18-15-36/h2-8H,9-19H2,1H3,(H,31,32)(H2,30,33,38)

InChI key: InChIKey=XLSYZSRXVVCHLS-UHFFFAOYSA-N

SMILES: O=C1C2=C(C=3C1=C(NC(NN4CCOCC4)=O)C=CC3)NN=C2C5=CC=C(CN6CCN(CCOC)CC6)C=C5

Synonyms:

• Urea, N-[1,4-dihydro-3-[4-[[4-(2-methoxyethyl)-1-piperazinyl]methyl]phenyl]-4-oxoindeno[1,2-c]pyrazol-5-yl]-N′-4-morpholinyl-
• 1-[3-[4-[[4-(2-Methoxyethyl)piperazin-1-yl]methyl]phenyl]-4-oxo-1H-indeno[1,2-c]pyrazol-5-yl]-3-morpholin-4-ylurea
• N-[1,4-Dihydro-3-[4-[[4-(2-methoxyethyl)-1-piperazinyl]methyl]phenyl]-4-oxoindeno[1,2-c]pyrazol-5-yl]-N′-4-morpholinylurea

RGB-286638 (free base)

CAS: 784210-88-4

Formula: C₂₉H₃₅N₇O₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 545.6327

Ref: IN-DA00G3PU

RGB-286638 free base

CAS: 784210-88-4

RGB-286638 free base

Purity: ≥95%

Molecular weight: 545.63g/mol

Ref: 54-BUP01954

RGB-286638 free base

CAS: 784210-88-4

RGB-286638 free base inhibits CDKs (1-5 nM), weaker on CDK7/6.

Formula: C₂₉H₃₅N₇O₄

Purity: 98% - 99.91%

Color and Shape: Solid

Molecular weight: 545.63

Ref: TM-T2378

RGB-286638 free base

CAS: 784210-88-4

RGB-286638 is a potent antitumor agent that inhibits the activity of actin filaments. It has been shown to inhibit tumor growth in mice with cancer and to have minimal toxicity. The mechanism by which RGB-286638 exerts its antitumor effects is not fully understood, but it may be related to its ability to bind to the Mcl-1 protein and inhibit the function of this protein. RGB-286638 also binds to DNA and inhibits enzymatic activity necessary for cellular proliferation. This drug has been shown to produce necrotic cell death in vitro with minimal effect on healthy cells.

Formula: C₂₉H₃₅N₇O₄

Purity: Min. 95%

Molecular weight: 545.63 g/mol

Ref: 3D-JGB21088