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CAS 78553-23-8

:

fmoc-L-aspartic acid 4-T-butyl 1-hydro-xysuccinimide) ester

Description:
Fmoc-L-aspartic acid 4-T-butyl 1-hydroxy-succinimide ester, with the CAS number 78553-23-8, is a chemical compound commonly used in peptide synthesis and bioconjugation. It features a protective Fmoc (9-fluorenylmethoxycarbonyl) group, which is widely utilized to protect amino groups during peptide synthesis. The presence of the aspartic acid moiety provides the compound with acidic properties, while the succinimide ester facilitates the formation of amide bonds with nucleophiles, making it useful for coupling reactions. The tert-butyl group enhances the compound's stability and solubility in organic solvents. This compound is typically employed in the synthesis of peptides and other biomolecules, allowing for selective modifications and functionalization. Its reactivity and stability under various conditions make it a valuable tool in organic and medicinal chemistry. Additionally, the compound's structure allows for easy removal of the Fmoc group under mild basic conditions, enabling the subsequent formation of peptide bonds. Overall, this compound is significant in the field of chemical biology and peptide chemistry.
Formula:C27H28N2O8
Synonyms:
  • Fmoc-Asp(OtBu)-OSu
  • Fmoc-Asp(OBut)-OSu
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