CAS 786-50-5

10-(Chloroacetyl)phenothiazine

Description:

10-(Chloroacetyl)phenothiazine is a chemical compound characterized by its phenothiazine backbone, which is a tricyclic structure containing sulfur and nitrogen atoms. This compound features a chloroacetyl group attached to the 10-position of the phenothiazine ring, which contributes to its reactivity and potential biological activity. It is typically a solid at room temperature and may exhibit moderate solubility in organic solvents. The presence of the chloroacetyl group can enhance its electrophilic properties, making it useful in various chemical reactions, including acylation and substitution reactions. This compound is of interest in medicinal chemistry due to its potential pharmacological properties, particularly in the development of antipsychotic and antimicrobial agents. Safety considerations should be taken into account, as compounds containing chlorine can pose health risks, and appropriate handling and disposal procedures should be followed. Overall, 10-(Chloroacetyl)phenothiazine serves as a valuable intermediate in organic synthesis and pharmaceutical research.

Formula: C₁₄H₁₀ClNOS

InChI: InChI=1S/C14H10ClNOS/c15-9-14(17)16-10-5-1-3-7-12(10)18-13-8-4-2-6-11(13)16/h1-8H,9H2

InChI key: InChIKey=NVRFGQJNKQLUPU-UHFFFAOYSA-N

SMILES: C(CCl)(=O)N1C=2C(SC=3C1=CC=CC3)=CC=CC2

Synonyms:

• 10-(Chloroacetyl)phenothiazine
• 10H-Phenothiazine, 10-(chloroacetyl)-
• 2-Chloro-1-(10H-phenothiazin-10-yl)ethan-1-one
• 2-Chloro-1-phenothiazin-10-yl-ethanone
• 2-Chloro-1-phenothiazin-10-ylethanone
• 2-chloro-1-(10H-phenothiazin-10-yl)ethanone
• Ethanone, 2-chloro-1-(10H-phenothiazin-10-yl)-
• N-(Chloroacetyl)phenothiazine
• NSC 239984
• NSC 71676
• Phenothiazine, 10-(chloroacetyl)-