CAS 78636-53-0

4-amino-1-(2-deoxy-2-fluoro-alpha-D-arabinofuranosyl)-5-methylpyrimidin-2(1H)-one

Description:

4-amino-1-(2-deoxy-2-fluoro-alpha-D-arabinofuranosyl)-5-methylpyrimidin-2(1H)-one, with the CAS number 78636-53-0, is a nucleoside analog that exhibits structural similarities to naturally occurring nucleosides. This compound features a pyrimidine base, specifically a 5-methylpyrimidin-2(1H)-one, which is substituted with an amino group at the 4-position and a deoxyfluoro-arabinofuranosyl moiety at the 1-position. The presence of the fluorine atom enhances its stability and bioactivity, making it of interest in medicinal chemistry, particularly in antiviral and anticancer research. The compound's unique structure allows it to interfere with nucleic acid synthesis, potentially inhibiting the replication of certain viruses or cancer cells. Its solubility, stability, and reactivity are influenced by the functional groups present, and it may exhibit specific interactions with biological targets, contributing to its pharmacological properties. Overall, this compound represents a significant area of study in the development of therapeutic agents.

Formula: C₁₀H₁₄FN₃O₄

InChI: InChI=1/C10H14FN3O4/c1-4-2-14(10(17)13-8(4)12)9-6(11)7(16)5(3-15)18-9/h2,5-7,9,15-16H,3H2,1H3,(H2,12,13,17)/t5-,6+,7-,9+/m1/s1

Synonyms:

• 2'-Fluoro-5-Methylarabino-Furanosylcytosine
• 2’-Deoxy-2’-fluoro-5-methyl-arabinocytidine, Anticancer agent
• 2'-Deoxy-2'-fluoro-5-Methyl-beta-D-arabinocytidine
• 2'-Deoxy-2'-fluoro-5-methyl-arabinocytidine
• 2(1H)-Pyrimidinone, 4-amino-1-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-5-methyl
• 2(1H)-Pyrimidinone, 4-amino-1-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-5-methyl-
• 2'-Deoxy-2'-fluoro-5-methyl-araobinocytidine
• 4-Amino-1-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-5-methyl-2(1H)-pyrimidinone

2'-Deoxy-2'-fluoro-5-methyl-arabinocytidine

CAS: 78636-53-0

Nucleoside Derivatives - Fluoro-modified nucleosides, Arabino-nucleosides,5-Modified pyrimidine nucleosides, 2’-Modified nucleosides; Drugs and Inhibitors;

Formula: C₁₀H₁₄FN₃O₄

Color and Shape: Solid

Molecular weight: 259.23

Ref: TM-TNU0184