CAS 78715-23-8

Norbuprenorphine

Description:

Norbuprenorphine is a semi-synthetic opioid derived from buprenorphine, primarily known for its role as a metabolite of buprenorphine in the human body. It exhibits analgesic properties and interacts with the opioid receptors in the central nervous system, specifically the mu-opioid receptor, albeit with a lower affinity compared to its parent compound. Norbuprenorphine is characterized by its ability to act as a partial agonist, which means it can activate opioid receptors but to a lesser extent than full agonists, potentially leading to a reduced risk of respiratory depression. This compound is often studied for its implications in pain management and opioid dependence treatment. In terms of physical properties, norbuprenorphine is typically a white to off-white solid, and it is soluble in organic solvents but has limited solubility in water. Its pharmacokinetics and dynamics are of significant interest in both clinical and research settings, particularly regarding its role in opioid metabolism and its potential therapeutic applications.

Formula:C₂₅H₃₅NO₄

InChI:InChI=1S/C25H35NO4/c1-21(2,3)22(4,28)16-13-23-8-9-25(16,29-5)20-24(23)10-11-26-17(23)12-14-6-7-15(27)19(30-20)18(14)24/h6-7,16-17,20,26-28H,8-13H2,1-5H3/t16-,17-,20-,22+,23-,24+,25-/m1/s1

InChI key:InChIKey=YOYLLRBMGQRFTN-IOMBULRVSA-N

SMILES:O(C)[C@@]12[C@]3([C@@]45[C@@]([C@@](CC6=C4C(O3)=C(O)C=C6)(NCC5)[H])(C[C@@]1([C@]([C@](C)(C)C)(C)O)[H])CC2)[H]

Synonyms:

N-De(cyclopropylmethyl)buprenorphine
6,14-Ethenomorphinan-7-methanol, α-(1,1-dimethylethyl)-4,5-epoxy-18,19-dihydro-3-hydroxy-6-methoxy-α-methyl-, (αS,5α,7α)-
Norbuprenorphine
6,14-Ethenomorphinan-7-methanol, α-(1,1-dimethylethyl)-4,5-epoxy-18,19-dihydro-3-hydroxy-6-methoxy-α-methyl-, [5α,7α(S)]-
(αS,5α,7α)-α-(1,1-Dimethylethyl)-4,5-epoxy-18,19-dihydro-3-hydroxy-6-methoxy-α-methyl-6,14-ethenomorphinan-7-methanol

Purity (%)

100

Found 10 products.

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Norbuprenorphine, 0.1mg/ml in Methanol
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 78715-23-8
Color and Shape:Single Solution
Ref: LP-BUP-982-FB-0.1LM
1ml
48.00€
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Norbuprenorphine 0.1 mg/ml in Methanol
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 78715-23-8
Color and Shape:Single Solution
Ref: 61-AMP0120.10-02
1ml
86.00€
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Norbuprenorphine
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 78715-23-8
Color and Shape:Neat
Ref: 61-FOR0120.10
5mg
468.00€
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Norbuprenorphine, 1mg/ml in Methanol
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 78715-23-8
Color and Shape:Single Solution
Ref: LP-BUP-982-FB-1LM
1ml
284.00€
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Norbuprenorphine 1.0 mg/ml in Methanol
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 78715-23-8
Color and Shape:Single Solution
Ref: 61-AMP0120.10-01
1ml
593.00€
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Norbuprenorphine
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 78715-23-8
Color and Shape:Neat
Ref: LP-BUP-982-FB-10
10mg
495.00€
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50mg
1,883.00€
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100mg
3,203.00€
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(2S)-2-(4,5α-Epoxy-3-hydroxy-6-methoxy-6α,14-ethano-14α-morphinan-7α-yl)-3,3-dimethylbutan-2-ol (Norbuprenorphine)
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 78715-23-8
Color and Shape:Neat
Ref: 86-MM0120.10
25mg
2,004.00€
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Norbuprenorphine
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 78715-23-8
Formula:C₂₅H₃₅NO₄
Color and Shape:White To Brown
Molecular weight:413.55
Ref: TR-N661300
1mg
100.00€
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5mg
412.00€
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Norbuprenorphine (1.0 mg/mL in Methanol)
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 78715-23-8
Formula:C₂₅H₃₅NO₄
Color and Shape:Colourless
Molecular weight:413.55
Ref: TR-KIT0695
1x1ml
1,027.00€
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Norbuprenorphine
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 78715-23-8
<p>Please enquire for more information about Norbuprenorphine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>
Formula:C₂₅H₃₅NO₄
Purity:Min. 95%
Molecular weight:413.55 g/mol
Ref: 3D-FN26431
1g
2,440.00€
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