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CAS 78739-01-2

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(2R)-2-amino-4-phosphonobutanoic acid

Description:
(2R)-2-amino-4-phosphonobutanoic acid, commonly known as APB, is a synthetic amino acid and a phosphonic acid derivative. It is characterized by the presence of both an amino group and a phosphonate group, which contributes to its unique biochemical properties. This compound is often studied for its role as a selective agonist for certain glutamate receptors, particularly in the context of neurological research. Its stereochemistry, indicated by the (2R) designation, suggests that it has a specific spatial arrangement that can influence its biological activity and interaction with receptors. APB is soluble in water, which facilitates its use in various biological assays and experiments. Additionally, it is important in the study of neuropharmacology and may have implications in understanding excitatory neurotransmission and related disorders. Due to its structural features, APB can also serve as a valuable tool in the development of therapeutic agents targeting glutamatergic signaling pathways.
Formula:C4H10NO5P
InChI:InChI=1/C4H10NO5P/c5-3(4(6)7)1-2-11(8,9)10/h3H,1-2,5H2,(H,6,7)(H2,8,9,10)/t3-/m1/s1
SMILES:C(CP(=O)(O)O)[C@H](C(=O)O)N
Synonyms:
  • Butanoic acid, 2-amino-4-phosphono-, (2R)-
  • (2R)-2-Amino-4-phosphonobutanoic acid
  • PSD-95/SAP90-binding protein 4
  • DLP4
  • D(-)-2-Amino-4-phosphonobutyric acidD-AP4
  • D(-)-2-AMINO-4-PHOSPHONOBUTANOIC ACID
  • RP5-977B1.6
  • D(-)-2-Amino-4-phosphonobutyric acid,97%
  • D-AP4
  • KIAA0964
  • See more synonyms
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