CAS 78756-33-9

ethyl 8-chloro-5-methyl-6-oxo-5,6-dihydro-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylate

Description:

Ethyl 8-chloro-5-methyl-6-oxo-5,6-dihydro-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylate is a complex organic compound characterized by its unique bicyclic structure, which incorporates both imidazole and benzodiazepine moieties. This compound features a chloro substituent at the 8-position and a methyl group at the 5-position, contributing to its chemical reactivity and potential biological activity. The presence of the ethyl ester group at the carboxylate position enhances its solubility and may influence its pharmacokinetic properties. The oxo group at the 6-position indicates a carbonyl functionality, which can participate in various chemical reactions, including nucleophilic attacks. This compound is of interest in medicinal chemistry, particularly for its potential therapeutic applications, possibly in the realm of anxiolytics or sedatives, due to the structural similarities with known benzodiazepine derivatives. Its CAS number, 78756-33-9, allows for precise identification in chemical databases and literature. Overall, this compound exemplifies the intricate interplay of structure and function in organic chemistry.

Formula: C₁₅H₁₄ClN₃O₃

InChI: InChI=1/C15H14ClN3O3/c1-3-22-15(21)13-12-7-18(2)14(20)10-6-9(16)4-5-11(10)19(12)8-17-13/h4-6,8H,3,7H2,1-2H3

SMILES: CCOC(=O)c1c2CN(C)C(=O)c3cc(ccc3n2cn1)Cl

Synonyms:

• 4H-Imidazo(1,5-a)(1,4)benzodiazepine-3-carboxylic acid, 8-chloro-5,6-dihydro-5-methyl-6-oxo-, ethyl ester
• Ethyl 8-chloro-5,6-dihydro-5-methyl-6-oxo-4H-imidazo(1,5-a)(1,4)benzodiazepine-3-carboxylate

Flumazenil EP impurity F

CAS: 78756-33-9

Formula: C₁₅H₁₄ClN₃O₃

Molecular weight: 319.75

Ref: 4Z-F-070021

8-Chloro-5,6-dihydro-5-methyl-6-oxo-4H-Imidazo[1,5-a][1,4]benzodiazepine-3-carboxylic Acid Ethyl Ester

Controlled Product

CAS: 78756-33-9

Impurity Flumazenil EP Impurity F
Applications 8-Chloro-5,6-dihydro-5-methyl-6-oxo-4H-Imidazo[1,5-a][1,4]benzodiazepine-3-carboxylic Acid Ethyl Ester is an impurity of Flumazenil (F500450), an imidazodiazepine which selectively blocks the central effects of classic benzodiazepines.
References Hunkeler, W., et al.: Nature, 290, 514 (1981), Pole, P., et al.: Arch. Pharmacol., 316, 317 (1981), Timm, U., et al.: Arzneim.-Forsch., 33, 358 (1983),

Formula: C₁₅H₁₄ClN₃O₃

Color and Shape: Neat

Molecular weight: 319.74

Ref: TR-C365485

Flumazenil EP Impurity F

CAS: 78756-33-9

Formula: C₁₅H₁₄ClN₃O₃

Molecular weight: 319.74

Ref: ST-EA-CP-F66016

Ro 15-1310

CAS: 78756-33-9

Ro 15-3505, a benzodiazepine receptor partial inverse agonist, has shown the ability to improve impaired recent memory of aged mice.

Formula: C₁₅H₁₄ClN₃O₃

Color and Shape: Solid

Molecular weight: 319.74

Ref: TM-T28558