CAS 78824-30-3

Garcinol (benzophenone)

Description:

Garcinol, also known as benzophenone, is a naturally occurring compound primarily derived from the fruit of the Garcinia indica plant. It is characterized by its polyphenolic structure, which contributes to its antioxidant properties. Garcinol exhibits a yellow to brown color and is soluble in organic solvents but has limited solubility in water. This compound is known for its potential health benefits, including anti-inflammatory, anticancer, and antimicrobial activities, making it of interest in both food and pharmaceutical industries. Additionally, garcinol has been studied for its ability to inhibit certain enzymes and its role in modulating various biological pathways. Its applications extend to being a natural preservative and a potential ingredient in cosmetic formulations due to its UV-absorbing properties. However, as with many bioactive compounds, further research is necessary to fully understand its mechanisms of action and potential therapeutic uses. Safety assessments are also crucial to determine any toxicological effects associated with its use.

Formula: C₃₈H₅₀O₆

InChI: InChI=1S/C38H50O6/c1-22(2)11-13-27(25(7)8)20-37-21-28(15-12-23(3)4)36(9,10)38(35(37)44,18-17-24(5)6)34(43)31(33(37)42)32(41)26-14-16-29(39)30(40)19-26/h11-12,14,16-17,19,27-28,39-40,42H,7,13,15,18,20-21H2,1-6,8-10H3/t27-,28+,37+,38-/m0/s1

InChI key: InChIKey=QDKLRKZQSOQWJQ-SMDXAGPFSA-N

SMILES: C([C@H](CC=C(C)C)C(C)=C)[C@]12C(=O)[C@](CC=C(C)C)(C(=O)C(C(=O)C3=CC(O)=C(O)C=C3)=C1O)C(C)(C)[C@H](CC=C(C)C)C2

Synonyms:

• (1R,5R,7R)-3-(3,4-Dihydroxybenzoyl)-4-hydroxy-8,8-dimethyl-1,7-bis(3-methyl-2-buten-1-yl)-5-[(2S)-5-methyl-2-(1-methylethenyl)-4-hexen-1-yl]bicyclo[3.3.1]non-3-ene-2,9-dione
• Bicyclo[3.3.1]non-3-ene-2,9-dione, 3-(3,4-dihydroxybenzoyl)-4-hydroxy-8,8-dimethyl-1,7-bis(3-methyl-2-butenyl)-5-[(2S)-5-methyl-2-(1-methylethenyl)-4-hexenyl]-, (1R,5R,7R)-
• Bicyclo[3.3.1]non-3-ene-2,9-dione, 3-(3,4-dihydroxybenzoyl)-4-hydroxy-8,8-dimethyl-1,7-bis(3-methyl-2-butenyl)-5-[5-methyl-2-(1-methylethenyl)-4-hexenyl]-, [1R-[1α,5α,5(S*),7β]]-
• Garcinol
• Garcinol (benzophenone)
• bicyclo[3.3.1]non-3-ene-2,9-dione, 3-(3,4-dihydroxybenzoyl)-4-hydroxy-8,8-dimethyl-1,7-bis(3-methyl-2-buten-1-yl)-5-[(2S)-5-methyl-2-(1-methylethenyl)-4-hexen-1-yl]-, (1R,5R,7R)-
• guttiferone E

Garcinol

CAS: 78824-30-3

Formula: C₃₈H₅₀O₆

Purity: 95%

Color and Shape: Solid

Molecular weight: 602.8000

Ref: IN-DA00G3CO

Amylase

CAS: 78824-30-3

Amylase

Purity: ≥95%

Ref: 54-BUP20470

γ-secretase modulator 3

CAS: 78824-30-3

γ-secretase modulator 3

Purity: ≥98%

Molecular weight: 434.53g/mol

Ref: 54-BUP20471

Garcinol

CAS: 78824-30-3

Formula: C₃₈H₅₀O₆

Molecular weight: 602.81

Ref: 4Z-G-225001

Garcinol

CAS: 78824-30-3

Garcinol: inhibits HATs/PCAF (IC50=7/5 μM), anti-inflammatory, anti-cancer, anti-cholinesterase (AChE IC50=0.66 μM, BChE IC50=7.39 μM).

Formula: C₃₈H₅₀O₆

Purity: 98.59%

Color and Shape: Solid

Molecular weight: 602.8

Ref: TM-T11366

Garcinol

Controlled Product

CAS: 78824-30-3

Applications Garcinol is a small molecule inhibitor of histone acetyltransferases. Used in cancer therapy. Garcinol, harvested from Garcinia indica.
References Oike, T. et al.: J. Rad. Res., 55, 613 (2014); Tsai, M. et al.: Mol. Nutr. Food Res., 58, 1820 (2014);

Formula: C₃₈H₅₀O₆

Color and Shape: Off-White

Molecular weight: 602.8

Ref: TR-G245425

Garcinol

CAS: 78824-30-3

Polyisoprenylated benzophenone from Garcinia indica; HAT inhibitor

Formula: C₃₈H₅₀O₆

Purity: Min. 97 Area-%

Color and Shape: Yellow Powder

Molecular weight: 602.8 g/mol

Ref: 3D-FG166571