CAS 78858-44-3

(2R)-3-(hexadecyloxy)-2-methoxypropyl 2-(trimethylammonio)ethyl phosphate

Description:

The chemical substance known as (2R)-3-(hexadecyloxy)-2-methoxypropyl 2-(trimethylammonio)ethyl phosphate, with the CAS number 78858-44-3, is a quaternary ammonium compound that exhibits amphiphilic properties due to its dual hydrophilic and hydrophobic characteristics. This compound features a long-chain hexadecyl group, which contributes to its lipophilicity, while the trimethylammonio group provides a positive charge, enhancing its solubility in polar solvents. The presence of the phosphate group further increases its hydrophilicity, making it suitable for various applications in biochemical and pharmaceutical fields, particularly in drug delivery systems and as a surfactant. Its structural configuration allows it to interact with biological membranes, potentially facilitating the transport of molecules across lipid bilayers. Additionally, this compound may exhibit antimicrobial properties, making it of interest in the development of antimicrobial agents. Overall, its unique structural features enable a range of functionalities in both research and industrial applications.

Formula: C₂₅H₅₄NO₆P

InChI: InChI=1/C25H54NO6P/c1-6-7-8-9-10-11-12-13-14-15-16-17-18-19-21-30-23-25(29-5)24-32-33(27,28)31-22-20-26(2,3)4/h25H,6-24H2,1-5H3/t25-/m1/s1

SMILES: CCCCCCCCCCCCCCCCOC[C@H](COP(=O)([O-])OCC[N+](C)(C)C)OC

Synonyms:

• ethanaminium, 2-[[[[(2R)-3-(hexadecyloxy)-2-methoxypropyl]oxy]hydroxyphosphinyl]oxy]-N,N,N-trimethyl-, inner salt

1-O-Hexadecyl-2-O-methyl-sn-glycero-3-phosphocholine

CAS: 78858-44-3

1-O-Hexadecyl-2-O-methyl-sn-glycero-3-phosphocholine is a useful scaffold, versatile building block, and useful intermediate that can be used in the synthesis of complex compounds. It is a high quality reagent and research chemical that can be used as a reaction component for speciality chemicals. 1-O-Hexadecyl-2-O-methyl-sn-glycero-3-phosphocholine has CAS number 788584443.

Formula: C₂₅H₅₄NO₆P

Purity: Min. 95 Area-%

Molecular weight: 495.67 g/mol

Ref: 3D-H-1844

1-O-Hexadecyl-2-O-methyl-sn-glycero-3-phosphocholine

CAS: 78858-44-3

1-O-Hexadecyl-2-O-methyl-sn-glycero-3-phosphocholine (HPC) is a phospholipid that is synthesized from the essential fatty acid linoleic acid. It has been shown to have an inhibitory effect on leukemia cells, which may be due to its ability to induce apoptosis by inducing the death of tumor cells and inhibiting protein synthesis. HPC also interacts synergistically with other agents such as phorbol esters, which can lead to increased cell death. This drug has been shown to have immunomodulatory effects in fibrosarcoma cells, where it inhibits tumor growth and induces apoptotic cell death. HPC binds to specific antigens and modulates immune responses through the inhibition of diacylglycerol production.

Formula: C₂₅H₅₄NO₆P

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 495.68 g/mol

Ref: 3D-FH177698

2-O-methyl PAF C-16

CAS: 78858-44-3

2-O-methyl PAF C-16 is a synthetic analog of platelet-activating factor (PAF) featuring a methyl group attached via an ether linkage at the sn-2 position. While the specific biological activities of 2-O-methyl PAF C-16 remain undercharacterized, studies with its C-18 counterpart have demonstrated its ability to modulate various biological processes. These processes include reducing plasma membrane fluidity and hindering the invasiveness of tumor cells in embryonic chick hearts. Furthermore, in rat astrocytes, the C-18 analog prompts the release of significant amounts of nitric oxide (NO) through a mechanism that involves the activation of nitric oxide synthase (NOS).

Formula: C₂₅H₅₄NO₆P

Color and Shape: Solid

Molecular weight: 495.7

Ref: TM-T84610