CAS 78859-42-4

5'-(4-fluorosulfonylbenzoyl)adenosine hydrochloride

Description:

5'-(4-Fluorosulfonylbenzoyl)adenosine hydrochloride is a chemical compound that belongs to the class of nucleoside analogs. It features an adenosine backbone, which is a key component of various biological molecules, including ATP. The presence of a 4-fluorosulfonylbenzoyl group enhances its reactivity and potential for biological activity, particularly in the context of enzyme inhibition or modulation. This compound is typically used in biochemical research, particularly in studies involving nucleoside metabolism and signaling pathways. Its hydrochloride form indicates that it is a salt, which can influence its solubility and stability in aqueous solutions. The fluorosulfonyl group is known for its electrophilic properties, making this compound a candidate for further chemical modifications or as a probe in biological assays. As with many chemical substances, handling should be done with care, considering potential toxicity and reactivity. Overall, 5'-(4-fluorosulfonylbenzoyl)adenosine hydrochloride serves as a valuable tool in the field of medicinal chemistry and pharmacology.

Formula: C₁₇H₁₇ClFN₅O₇S

InChI: InChI=1/C17H16FN5O7S.ClH/c18-31(27,28)9-3-1-8(2-4-9)17(26)29-5-10-12(24)13(25)16(30-10)23-7-22-11-14(19)20-6-21-15(11)23;/h1-4,6-7,10,12-13,16,24-25H,5H2,(H2,19,20,21);1H/t10-,12-,13-,16-;/m1./s1

SMILES: c1cc(ccc1C(=O)OC[C@@H]1[C@H]([C@H]([C@H](n2cnc3c(N)ncnc23)O1)O)O)S(=O)(=O)F.Cl

Synonyms:

• 5'-(4-(Fluorosulfonyl)benzoyl)adenosine
• 5'-(Para-(fluorosulfonyl)benzoyl)adenosine
• 5-Fsba
• 5'-O-[4-(fluorosulfonyl)benzoyl]adenosine hydrochloride (1:1)

FSBA hydrochloride

CAS: 78859-42-4

FSBA hydrochloride

Purity: ≥95%

Molecular weight: 489.86g/mol

Ref: 54-BUP22254

5''-(4-Fluorosulfonylbenzoyl)adenosine hydrochloride

CAS: 78859-42-4

Formula: C₁₇H₁₆FN₅O₇S·HCl

Purity: (HPLC) ≥ 98.0%

Color and Shape: White to off-white powder

Molecular weight: 489.86

Ref: 7W-GN5415

5'-(4-Fluorosulfonylbenzoyl)adenosine HCI

CAS: 78859-42-4

5'-(4-Fluorosulfonylbenzoyl)adenosine HCI is an inhibitor of adenosine deaminase. It has been used as a tool in the diagnosis of autoimmune diseases. 5'-(4-Fluorosulfonylbenzoyl)adenosine HCI binds to the α subunit of mitochondrial ATPase and inhibits its function, leading to a drop in mitochondrial membrane potential. This can be measured by electron paramagnetic resonance spectroscopy, which can detect changes in redox potentials and the presence of disulfide bonds. 5'-(4-Fluorosulfonylbenzoyl)adenosine HCI also binds to DNA synthetase and metal chelate, inhibiting protein synthesis.
5'-(4-Fluorosulfonylbenzoyl)adenosine HCI has been shown to inhibit various enzymes such as phosphofructokinase, glycogen phosph

Formula: C₁₇H₁₇ClFN₅O₇S

Purity: Min. 97.0 Area-%

Molecular weight: 489.86 g/mol

Ref: 3D-W-203807

5'-(4-Fluorosulfonylbenzoyl)adenosine HCI

CAS: 78859-42-4

ATP analog; covalent inhibitor of anthrax edema factor

Formula: C₁₇H₁₇ClFN₅O₇S

Purity: Min. 95%

Color and Shape: White Off-White Powder

Molecular weight: 489.86 g/mol

Ref: 3D-NF08012

FSBA hydrochloride

CAS: 78859-42-4

FSBA hydrochloride(5'-p-Fluorosulfonylbenzoyladenosine) is an ATP analogue serving as an affinity probe for the ATP site of Na/K-ATPase.

Formula: C₁₇H₁₇ClFN₅O₇S

Purity: 97.96%

Color and Shape: Solid

Molecular weight: 489.86

Ref: TM-T27391