D-Streptamine, with the CAS number 78874-52-9, is a complex aminoglycoside antibiotic characterized by its unique glycosidic structure. It features a D-glucopyranosyl moiety linked to a 3-deoxy-3-(methylamino)-β-L-arabinopyranosyl unit through a (1→4) and (1→6) linkage, respectively. This compound exhibits antibacterial properties, primarily by inhibiting protein synthesis in susceptible bacteria, making it effective against a range of Gram-negative and some Gram-positive organisms. The presence of amino groups contributes to its solubility and interaction with bacterial ribosomes. D-Streptamine is often studied for its role in antibiotic resistance mechanisms and its potential therapeutic applications. Its structural complexity and functional groups also make it a subject of interest in medicinal chemistry, particularly in the design of new antibiotics. As with many aminoglycosides, it may exhibit nephrotoxicity and ototoxicity, necessitating careful consideration in clinical use. Overall, D-streptamine represents a significant compound in the field of antibiotic research and development.

D-Streptamine, O-6-amino-6-deoxy-α-D-glucopyranosyl-(1→4)-O-[3-deoxy-3-(methylamino)-β-L-arabinopyranosyl-(1→6)]-

78874-52-9: D-Streptamine, with the CAS number 78874-52-9, is a complex aminoglycoside antibiotic characterized by its unique glycosidic structure. It features a D-glucopyranosyl moiety linked to a 3-deoxy-3-(methylamino)-β-L-arabinopyranosyl unit through a (1→4) and (1→6) linkage, respectively. This compound exhibits antibacterial properties, primarily by inhibiting protein synthesis in susceptible bacteria, making it effective against a range of Gram-negative and some Gram-positive organisms. The presence of amino groups contributes to its solubility and interaction with bacterial ribosomes. D-Streptamine is often studied for its role in antibiotic resistance mechanisms and its potential therapeutic applications. Its structural complexity and functional groups also make it a subject of interest in medicinal chemistry, particularly in the design of new antibiotics. As with many aminoglycosides, it may exhibit nephrotoxicity and ototoxicity, necessitating careful consideration in clinical use. Overall, D-streptamine represents a significant compound in the field of antibiotic research and development.

<p>2-Hydroxygentamicin A3 is an aminoglycoside antibiotic effective against both Gram-positive and Gram-negative bacteria.</p>

CAS 78874-52-9

D-Streptamine, O-6-amino-6-deoxy-α-D-glucopyranosyl-(1→4)-O-[3-deoxy-3-(methylamino)-β-L-arabinopyranosyl-(1→6)]-

2-Hydroxygentamicin A3

Ref: TM-TN10530