CAS 788824-64-6

Phenol,4-[4-(2-aminoethyl)-2-iodophenoxy]-, hydrochloride (1:1)

Description:

Phenol, 4-[4-(2-aminoethyl)-2-iodophenoxy]-, hydrochloride (1:1) is a chemical compound characterized by its complex structure, which includes a phenolic group and an aminoethyl side chain substituted with an iodine atom. This compound typically appears as a white to off-white solid and is soluble in water due to the presence of the hydrochloride salt form, which enhances its solubility and stability. The aminoethyl group suggests potential biological activity, possibly interacting with various biological targets, making it of interest in medicinal chemistry. The iodine substitution may also impart unique properties, such as increased lipophilicity or altered reactivity. As a hydrochloride salt, it is likely to exhibit improved handling characteristics and stability compared to its free base form. Safety data should be consulted, as compounds containing iodine and amino groups can pose specific health risks. Overall, this compound's unique structural features may contribute to its utility in research and potential therapeutic applications.

Formula: C₁₄H₁₄INO₂ClH

Synonyms:

• Phenol,4-[4-(2-aminoethyl)-2-iodophenoxy]-, hydrochloride (9CI)
• 3-Iodothyronamine hydrochloride

3-Iodothyronamine (hydrochloride)

CAS: 788824-64-6

3-Iodothyronamine, from thyroxine, targets TAAR1 to modulate thyroid effects, lipid/glucose use, and may induce medical hibernation.

Formula: C₁₄H₁₅ClINO₂

Color and Shape: Solid

Molecular weight: 391.63

Ref: TM-T35839

Thyroxamine Impurity 1 HCl

CAS: 788824-64-6

Formula: C₁₄H₁₄INO₂·HCl

Molecular weight: 355.18 36.46

Ref: 4Z-T-4237

3-Iodothyronamine Hydrochloride

Controlled Product

CAS: 788824-64-6

Applications 3-Iodothyronamine is a novel metabolite of thyroid hormone (TH). 3-Iodothyronamine (T1AM) is an endogenous and rapid-acting derivative of thyroid hormone. It has alos been found to increase food intake in rodents.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Davis, P., et al.: Thyroid, 6, 497 (1996), Falkenstein, E., et al.: Pharmacol. Rev., 52, 513 (2000), Yen, P., et al.: Physiol. Rev., 81, 1097 (2001), Pinna, G., et al.: Endocrinology, 143, 1789 (2002), Dhillo et al.; Diabetes, Obesity & Metabolism (2008), 10(2), 167-70

Formula: C₁₄H₁₄INO₂·ClH

Color and Shape: Neat

Molecular weight: 391.63

Ref: TR-I720500

3-Iodothyronamine (4-Hydroxyphenyl-13C6) Hydrochloride

Controlled Product

CAS: 788824-64-6

Applications 3-Iodothyronamine (4-Hydroxyphenyl-13C6) Hydrochloride is an isotopic analog of 3-Iodothyronamine Hydrochloride (I720500), a novel metabolite of thyroid hormone.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Davis, P., et al.: Thyroid, 6, 497 (1996); Falkenstein, E., et al.: Pharmacol. Rev., 52, 513 (2000); Yen, P., et al.: Physiol. Rev., 81, 1097 (2001); Pinna, G., et al.: Endocrinology, 143, 1789 (2002); Dhillo et al.; Diabetes, Obesity & Metabolism, 10, 167-70 (2008);

Formula: C₈₁₃C₆H₁₄INO₂•(HCl)

Color and Shape: Neat

Molecular weight: 361.133646

Ref: TR-I720501

3-Iodothyronamine Hydrochloride

Controlled Product

CAS: 788824-64-6

3-Iodothyronamine Hydrochloride is a thyroid hormone that has been shown to activate the camp-dependent protein kinase pathway in vitro. 3-Iodothyronamine Hydrochloride has also been found to have agonist binding activity at amine receptors, and this may be due to its structural similarity with endogenous amines. In addition, 3-Iodothyronamine Hydrochloride has been shown to bind to the human thyroid hormone receptor and inhibit proopiomelanocortin (POMC) expression. It is believed that 3-iodothyronamine hydrochloride may function as a competitive antagonist of thyroxine or triiodothyronine binding to the nuclear thyroid hormone receptor complex, resulting in decreased levels of these hormones. This drug has also been shown to have physiological relevance by being present in human cerebrospinal fluid (CSF).

Formula: C₁₄H₁₅ClINO₂

Purity: Min. 95%

Molecular weight: 391.63 g/mol

Ref: 3D-NGB82464

Thyroxamine Impurity 1

CAS: 788824-64-6

Formula: C₁₄H₁₄INO₂HCl

Molecular weight: 355.18 : 36.46

Ref: ST-EA-CP-L18061